N
Nicholas D. Gold
Researcher at Concordia University
Publications - 13
Citations - 712
Nicholas D. Gold is an academic researcher from Concordia University. The author has contributed to research in topics: Saccharomyces cerevisiae & Aromatic amino acids. The author has an hindex of 9, co-authored 12 publications receiving 577 citations.
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Journal ArticleDOI
Global View of the Clostridium thermocellum Cellulosome Revealed by Quantitative Proteomic Analysis
TL;DR: The results support the existing theory that expression of scaffoldin-related proteins is coordinately regulated by a catabolite repression type of mechanism, as well as the prior observation that xylanase expression is subject to a growth rate-independent type of regulation.
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Building a global alliance of biofoundries
Nathan J. Hillson,Mark X. Caddick,Yizhi Cai,Jose A. Carrasco,Matthew Wook Chang,N Curach,David J. Bell,Rosalind Le Feuvre,Douglas C. Friedman,Xiongfei Fu,Nicholas D. Gold,Markus J. Herrgård,Maciej B. Holowko,Maciej B. Holowko,Maciej B. Holowko,James R. Johnson,Richard A. Johnson,Jay D. Keasling,Richard I. Kitney,Akihiko Kondo,Chenli Liu,Vincent J. J. Martin,Filippo Menolascina,Chiaki Ogino,Nicola J. Patron,Marilene Pavan,Chueh Loo Poh,Isak S. Pretorius,Susan J. Rosser,Nigel S. Scrutton,Marko Storch,Hille Tekotte,Evelyn Travnik,Claudia E. Vickers,Claudia E. Vickers,Wen Shan Yew,Ying-Jin Yuan,Huimin Zhao,Paul S. Freemont +38 more
TL;DR: Biofoundries provide an integrated infrastructure to enable the rapid design, construction, and testing of genetically reprogrammed organisms for biotechnology applications and research.
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Metabolic engineering of a tyrosine-overproducing yeast platform using targeted metabolomics
Nicholas D. Gold,Christopher M. Gowen,Francois-Xavier Lussier,Sarat C. Cautha,Radhakrishnan Mahadevan,Vincent J. J. Martin +5 more
TL;DR: The genome-scale metabolic model identified design strategies that have the potential to improve availability of erythrose 4-phosphate for DAHP synthase and cofactor availability for prephenate dehydrogenase and provide recommendations for further improvement of aromatic amino acid biosynthesis in S. cerevisiae.
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Sequential O-methylation of tricetin by a single gene product in wheat.
TL;DR: This is the first report of a gene product that catalyzes three sequential O-methylations of a flavonoid substrate, and the sequential order of tricetin methylation by TaOMT2 is envisaged to proceed via its 3'-mono--->3',5'-di- and trimethyl ether derivatives.
Journal ArticleDOI
Pyrenoid functions revealed by proteomics in Chlamydomonas reinhardtii.
Yu Zhan,Christophe H. Marchand,Alexandre Maes,Adeline Mauries,Yi Sun,James S. Dhaliwal,James Uniacke,Simon Arragain,Heng Jiang,Nicholas D. Gold,Vincent J. J. Martin,Stéphane D. Lemaire,William Zerges +12 more
TL;DR: Using radioisotope pulse labeling experiments, it is shown that pyrenoid-associated ribosomes could be engaged in the localized synthesis of the large subunit of Rubisco, supporting the long-standing hypothesis that the pyrenoids is a hub for metabolism.