N
Nancy Francoeur
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 36
Citations - 2544
Nancy Francoeur is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 12, co-authored 26 publications receiving 1888 citations. Previous affiliations of Nancy Francoeur include Beth Israel Deaconess Medical Center & New York University.
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Journal ArticleDOI
Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.
Panagiotis A. Konstantinopoulos,Dimitrios Spentzos,Beth Y. Karlan,Toshiyasu Taniguchi,Elena Fountzilas,Nancy Francoeur,Douglas A. Levine,Stephen A. Cannistra +7 more
TL;DR: The BRCAness profile correlates with responsiveness to platinum and PARP inhibitors and identifies a subset of sporadic patients with improved outcome and is validated in 70 patients enriched for sporadic disease.
Journal ArticleDOI
Introductions and early spread of SARS-CoV-2 in the New York City area.
Ana S. Gonzalez-Reiche,Matthew M. Hernandez,Mitchell J. Sullivan,Brianne Ciferri,Hala Alshammary,Ajay Obla,Shelcie Fabre,Giulio Kleiner,Jose Polanco,Zenab Khan,Bremy Alburquerque,Adriana van de Guchte,Jayeeta Dutta,Nancy Francoeur,Betsaida Salom Melo,Irina Oussenko,Gintaras Deikus,Juan C. Diaz Soto,Shwetha Hara Sridhar,Ying-Chih Wang,Kathryn Twyman,Andrew Kasarskis,Andrew Kasarskis,Deena R. Altman,Melissa Smith,Robert Sebra,Judith A. Aberg,Florian Krammer,Adolfo García-Sastre,Marta Luksza,Gopi Patel,Alberto Paniz-Mondolfi,Melissa R. Gitman,Emilia Mia Sordillo,Viviana Simon,Viviana Simon,Harm van Bakel +36 more
TL;DR: To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, the virus that causes coronavirus disease 2019 (COVID-19) was sequenced in patients seeking care at the Mount Sinai Health System.
Journal ArticleDOI
The PsychENCODE project
Schahram Akbarian,Chunyu Liu,James A. Knowles,Flora M. Vaccarino,Peggy J. Farnham,Gregory E. Crawford,Andrew E. Jaffe,Dalila Pinto,Stella Dracheva,Daniel H. Geschwind,Jonathan Mill,Jonathan Mill,Angus C. Nairn,Alexej Abyzov,Sirisha Pochareddy,Shyam Prabhakar,Sherman M. Weissman,Patrick F. Sullivan,Matthew W. State,Zhiping Weng,Mette A. Peters,Kevin P. White,Mark Gerstein,Anahita Amiri,Chris Armoskus,Allison E. Ashley-Koch,Taejeong Bae,Andrea Beckel-Mitchener,Benjamin P. Berman,Gerhard A. Coetzee,Gianfilippo Coppola,Nancy Francoeur,Menachem Fromer,Robert Gao,Kay Grennan,Jennifer Herstein,David H. Kavanagh,Nikolay A. Ivanov,Yan Jiang,Robert R. Kitchen,Alexey Kozlenkov,Marija Kundakovic,Mingfeng Li,Zhen Li,Shuang Liu,Lara M. Mangravite,Eugenio Mattei,Eirene Markenscoff-Papadimitriou,Fabio C. P. Navarro,Nicole North,Larsson Omberg,David M. Panchision,Neelroop N. Parikshak,Jeremie Poschmann,Amanda J. Price,Michael J. Purcaro,Timothy E. Reddy,Panos Roussos,Shannon Schreiner,Soraya Scuderi,Robert Sebra,Mikihito Shibata,Annie W. Shieh,Mario Skarica,Wenjie Sun,Vivek Swarup,Amber Thomas,Junko Tsuji,Harm van Bakel,Daifeng Wang,Yongjun Wang,Kai Wang,Donna M. Werling,A. Jeremy Willsey,Heather Witt,Hyejung Won,Chloe C. Y. Wong,Chloe C. Y. Wong,Gregory A. Wray,Emily Wu,Xuming Xu,Lijing Yao,Geetha Senthil,Thomas Lehner,Pamela Sklar,Nenad Sestan +85 more
TL;DR: The PsychENCODE project aims to produce a public resource of multidimensional genomic data using tissue- and cell type–specific samples from approximately 1,000 phenotypically well-characterized, high-quality healthy and disease-affected human post-mortem brains, as well as functionally characterize disease-associated regulatory elements and variants in model systems.
Journal ArticleDOI
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.
Solveig K. Sieberts,Thanneer M. Perumal,Minerva M. Carrasquillo,Mariet Allen,Joseph S. Reddy,Gabriel E. Hoffman,Kristen K. Dang,John N. Calley,Phillip J. Ebert,James A. Eddy,Xue Wang,Anna K. Greenwood,Sara Mostafavi,Sara Mostafavi,S Akbarian,J Bendl,M S Breen,K Brennand,L Brown,A Browne,J D Buxbaum,A Charney,Andrew Chess,Couto L,Gregory E. Crawford,Devillers O,Bernie Devlin,Amanda Dobbyn,E Domenici,M Filosi,E Flatow,Nancy Francoeur,John F. Fullard,S E Gil,Kiran Girdhar,A Gulyás-Kovács,R.E. Gur,C G Hahn,Vahram Haroutunian,Mads E. Hauberg,Laura M. Huckins,Rivka Jacobov,Y Jiang,Jessica S. Johnson,Bibi Kassim,Y Kim,Lambertus Klei,Robin Kramer,Mario Lauria,Thomas Lehner,David A. Lewis,Barbara K. Lipska,Kelsey S. Montgomery,R Park,C Rosenbluh,Panagiotis Roussos,Douglas M. Ruderfer,G Senthil,Hardik Shah,Laura G. Sloofman,L Song,E Stahl,P.F. Sullivan,R Visintainer,J Wang,Y C Wang,Jennifer Wiseman,E Xia,W Zhang,Elizabeth Zharovsky,L Addis,S N Addo,David C. Airey,Matthias Arnold,David A. Bennett,Y Bi,K Biber,Colette Blach,E Bradhsaw,Paul Brennan,R Canet-Aviles,S Cao,A Cavalla,Yooree Chae,W W Chen,J Cheng,David A. Collier,J L Dage,Eric B. Dammer,J W Davis,John B. Davis,Derek Drake,D Duong,Brian J. Eastwood,Michelle E. Ehrlich,B Ellingson,B W Engelmann,S Esmaeelinieh,Daniel Felsky,Cory C. Funk,Chris Gaiteri +100 more
TL;DR: A colocalization analysis is applied to identify genes underlying the GWAS association peaks for schizophrenia and identify a potentially novel gene colocalized with lncRNA RP11-677M14.
Journal ArticleDOI
Keap1 mutations and Nrf2 pathway activation in epithelial ovarian cancer.
Panagiotis A. Konstantinopoulos,Dimitrios Spentzos,Elena Fountzilas,Nancy Francoeur,Srisowmya Sanisetty,Alexandros P. Grammatikos,Jonathan L. Hecht,Stephen A. Cannistra +7 more
TL;DR: Patients with evidence of Nrf2 pathway activation had fewer complete clinical responses to platinum-based therapy, were enriched for platinum resistance, and had shorter median overall survival compared with those who did not show evidence of EOC pathway activation.