P
Philippe Bulois
Researcher at French Institute of Health and Medical Research
Publications - 45
Citations - 4383
Philippe Bulois is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Crohn's disease & Cancer. The author has an hindex of 14, co-authored 45 publications receiving 3914 citations. Previous affiliations of Philippe Bulois include Katholieke Universiteit Leuven.
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Journal ArticleDOI
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease
Arlette Darfeuille-Michaud,Jerome Boudeau,Philippe Bulois,Christel Neut,Anne-Lise Glasser,Nicolas Barnich,Marie-Agnès Bringer,Alexander Swidsinski,Laurent Beaugerie,Jean-Frederic Colombel +9 more
TL;DR: AIEC strains are associated specifically with ileal mucosa in CD, and the abilities of E. coli strains to invade epithelial cells and to survive and replicate within macrophages were assessed using the gentamicin protection assay.
Journal ArticleDOI
Development and validation of a new, simplified endoscopic activity score for Crohn's disease: the SES-CD
Marco Daperno,Geert D'Haens,Gert Van Assche,Filip Baert,Philippe Bulois,Vincent Maunoury,Raffaello Sostegni,Rodolfo Rocca,Angelo Pera,A.M. Gevers,Jean-Yves Mary,Jean-Frederic Colombel,Paul Rutgeerts +12 more
TL;DR: The aim of this study was to develop and to prospectively validate a simpler endoscopic score of disease activity, the Simple Endoscopic Score for Crohn's Disease, which was correlated to clinical parameters and serum C-reactive protein level.
Journal ArticleDOI
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma.
Christel Rousseaux,Bruno Lefebvre,Laurent Dubuquoy,Philippe Lefebvre,Olivier Romano,Johan Auwerx,Daniel Metzger,Walter Wahli,Béatrice Desvergne,Gian Carlo Naccari,Philippe Chavatte,Amaury Farce,Philippe Bulois,Antoine Cortot,Jean-Frederic Colombel,Pierre Desreumaux +15 more
TL;DR: PPAR-γ is identified as a target of 5-ASA underlying antiinflammatory effects in the colon, and its activities are associated with the recruitment of coactivators and the activation of a peroxisome-proliferator response element–driven gene.
Journal ArticleDOI
Changes in the bacterial flora of the neoterminal ileum after ileocolonic resection for Crohn’s disease
Christel Neut,Philippe Bulois,Pierre Desreumaux,Jeanne-Marie Membré,E Lederman,Luc Gambiez,Antoine Cortot,P. Quandalle,Herbert J. Van Kruiningen,Jean-Frederic Colombel +9 more
TL;DR: The data suggest that increases in the populations of specific bacteria such as E. coli, enterococci, bacteroides, and fusobacteria may be important in postoperative recurrence of Crohn's disease.
Journal ArticleDOI
Endoscopy and antiplatelet agents. European Society of Gastrointestinal Endoscopy (ESGE) Guideline
Christian Boustière,Andrew Veitch,Geoffroy Vanbiervliet,Philippe Bulois,Pierre Henri Deprez,A. Laquière,René Laugier,Gilles Lesur,Patrick Mosler,B Nalet,Bertrand Napoleon,Bjorn Rembacken,N Ajzenberg,J P Collet,Todd H. Baron,J-M Dumonceau +15 more
TL;DR: This guideline makes graded, evidence-based, recommendations for the management of APA for all currently performed endoscopic procedures.