P
Pieter E. Postmus
Researcher at Leiden University Medical Center
Publications - 390
Citations - 26022
Pieter E. Postmus is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 81, co-authored 384 publications receiving 24039 citations. Previous affiliations of Pieter E. Postmus include Vanderbilt University Medical Center & VU University Medical Center.
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Journal ArticleDOI
The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours.
Peter Goldstraw,John Crowley,Kari Chansky,Dorothy J. Giroux,Patti A. Groome,Ramón Rami-Porta,Pieter E. Postmus,Valerie W. Rusch,Leslie H. Sobin +8 more
TL;DR: Suggestions include additional cutoffs for tumor size, with tumors >7 cm moving from T2 to T3; reassigning the category given to additional pulmonary nodules in some locations; and reclassifying pleural effusion as an M descriptor.
Journal ArticleDOI
Prophylactic Cranial Irradiation in Extensive Small-Cell Lung Cancer
Berend J. Slotman,Corinne Faivre-Finn,G.W.P.M. Kramer,E.M. Rankin,Michael Snee,Matthew Hatton,Pieter E. Postmus,Laurence Collette,Elena Musat,Suresh Senan +9 more
TL;DR: Prophylactic cranial irradiation reduces the incidence of symptomatic brain metastases and prolongs disease-free and overall survival and did not have a clinically significant effect on global health status.
Journal ArticleDOI
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
Nicholas McGranahan,Rachel Rosenthal,Crispin T. Hiley,Crispin T. Hiley,Andrew J. Rowan,Thomas B.K. Watkins,Gareth A. Wilson,Gareth A. Wilson,Nicolai Juul Birkbak,Nicolai Juul Birkbak,Selvaraju Veeriah,Peter Van Loo,Peter Van Loo,Javier Herrero,Charles Swanton,Charles Swanton,Mariam Jamal-Hanjani,Seema Shafi,Justyna Czyzewska-Khan,Diana Johnson,Joanne Laycock,Leticia Bosshard-Carter,Pat Gorman,Robert E. Hynds,Gareth A. Wilson,Stuart Horswell,Richard Mitter,Mickael Escudero,Aengus Stewart,Andrew Rowan,Hang Xu,Samra Turajlic,Crispin T. Hiley,Christopher Abbosh,Jacki Goldman,Richard Kevin Stone,Tamara Denner,Nik Matthews,Greg Elgar,Sophia Ward,Marta Costa,Sharmin Begum,Ben Phillimore,Tim Chambers,Emma Nye,Sofia Graca,Maise Al Bakir,Kroopa Joshi,Andrew Furness,Assma Ben Aissa,Yien Ning Sophia Wong,Andy Georgiou,Sergio A. Quezada,John A. Hartley,Helen Lowe,David Lawrence,Martin Hayward,Nikolaos Panagiotopoulos,Shyam Kolvekar,Mary Falzon,Elaine Borg,Teresa Marafioti,Celia Simeon,Gemma Hector,Amy Smith,Marie Aranda,Marco Novelli,Dahmane Oukrif,Sam M. Janes,Ricky Thakrar,Martin Forster,Tanya Ahmad,Siow Ming Lee,Dionysis Papadatos-Pastos,Dawn Carnell,Ruheena Mendes,Jeremy George,Neal Navani,Asia Ahmed,Magali Taylor,Junaid Choudhary,Yvonne Summers,Raffaele Califano,Paul D. Taylor,Rajesh Shah,Piotr Krysiak,Kendadai Rammohan,Eustace Fontaine,Richard Booton,Matthew Evison,Phil Crosbie,Stuart Moss,Faiza Idries,Leena Dennis Joseph,Paul N. Bishop,Anshuman Chaturved,Anne Marie Quinn,H. Doran,Angela Leek,Phil Harrison,Katrina Moore,Rachael Waddington,Juliette Novasio,Fiona H Blackhall,Jane Rogan,Elaine Smith,Caroline Dive,Jonathan Tugwood,Ged Brady,Dominic G. Rothwell,Francesca Chemi,Jackie Pierce,Sakshi Gulati,Babu Naidu,Gerald Langman,Simon Trotter,Mary Bellamy,Hollie Bancroft,Amy Kerr,Salma Kadiri,Joanne Webb,Gary Middleton,Madava Djearaman,Dean A. Fennell,Jacqui Shaw,John Le Quesne,David A. Moore,Apostolos Nakas,Sridhar Rathinam,William Monteiro,Hilary Marshall,Louise Nelson,Jonathan Bennett,Joan K. Riley,Lindsay Primrose,Luke Martinson,Girija Anand,Sajid A. Khan,Anita Amadi,Marianne Nicolson,Keith M. Kerr,Shirley Palmer,Hardy Remmen,Joy Miller,Keith Buchan,Mahendran Chetty,Lesley Gomersall,Jason F. Lester,A Edwards,Fiona Morgan,Haydn Adams,Helen Davies,Malgorzata Kornaszewska,Richard Attanoos,Sara Lock,Azmina Verjee,Mairead MacKenzie,Maggie Wilcox,Harriet Bell,Allan Hackshaw,Yenting Ngai,Sean W. Smith,N.H. Gower,Christian H. Ottensmeier,Serena Chee,Benjamin Johnson,Aiman Alzetani,Emily Shaw,Eric Lim,Paulo Loureiro de Sousa,Monica Tavares Barbosa,Alex Bowman,Simon Jordan,Alexandra Rice,H. Raubenheimer,Chiara Proli,Maria Elena Cufari,John Carlo Ronquillo,Angela Kwayie,Harshil Bhayani,Morag Hamilton,Yusura Bakar,Natalie Mensah,Lyn Ambrose,Anand Devaraj,Silviu Buderi,Jonathan Finch,Leire Azcarate,Hema Chavan,Sophie Green,Hillaria Mashinga,Andrew G. Nicholson,Kelvin Lau,Michael Sheaff,Peter Schmid,John Conibear,Veni Ezhil,Babikir Ismail,Melanie Irvin-Sellers,Vineet Prakash,Peter Russell,Teresa Light,Tracey Horey,Sarah Danson,Jonathan Bury,John G. Edwards,Jennifer Hill,S. Matthews,Yota Kitsanta,Kim Suvarna,Patricia Fisher,Allah Dino Keerio,Michael Shackcloth,John Gosney,Pieter E. Postmus,Sarah Feeney,Julius Asante-Siaw,Hugo J.W.L. Aerts,Stefan C. Dentro,Christophe Dessimoz +219 more
TL;DR: It is found that HLA LOH occurs in 40% of non-small-cell lung cancers (NSCLCs) and is associated with a high subclonal neoantigen burden, APOBEC-mediated mutagenesis, upregulation of cytolytic activity, and PD-L1 positivity.
Journal ArticleDOI
Effectiveness of positron emission tomography in the preoperative assessment of patients with suspected non-small-cell lung cancer: the PLUS multicentre randomised trial.
Harm van Tinteren,Otto S. Hoekstra,Egbert F. Smit,Jan H.A.M. Van Den Bergh,Ad J.M. Schreurs,Roland A. L. M. Stallaert,Piet C.M. Van Velthoven,Emile F.I. Comans,Fred W. Diepenhorst,Paul Verboom,Johan C. van Mourik,Pieter E. Postmus,Maarten Boers,Gerrit J.J. Teule +13 more
TL;DR: Addition of PET to conventional workup prevented unnecessary surgery in one out of five patients with suspected non-small-cell lung cancer, and the primary outcome measure was futile thoracotomy.
Journal ArticleDOI
Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension.
Serge A. van Wolferen,J.T. Marcus,Anco Boonstra,Koen M. Marques,Jean G.F. Bronzwaer,Marieke D. Spreeuwenberg,Pieter E. Postmus,Anton Vonk-Noordegraaf +7 more
TL;DR: The RV contains prognostic information in IPAH and a large RV volume, low SV, and a reduced LV volume are strong independent predictors of mortality and treatment failure.