R. Krishna Murthy Karuturi

TL;DR: It is proposed that chromatin interactions constitute a primary mechanism for regulating transcription in mammalian genomes and is described as a new strategy, chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) for the de novo detection of global Chromatin interactions.

TL;DR: It is proposed that an extensive, pluripotency-specific recruitment profile lends REST a key role in the maintenance of the ESC phenotype.

TL;DR: To investigate cell cycle-regulated transcriptional programs in the fission yeast Schizosaccharomyces pombe, a whole-genome oligonucleotide-based DNA microarray was developed and found approximately 140 genes that are cell cycle regulated in both yeasts, suggesting that these genes may play an evolutionarily conserved role in regulation of cell cycle -specific processes.

TL;DR: Microarray analysis demonstrated a significant correlation between the expression signature and growth phenotype of kinase mutants tested, and proposed the existence of four major signaling pathways that are involved in the response to 17 stresses tested.

TL;DR: The results suggest that the Bp accessory genome is likely to play an important role in microbial adaptation and virulence, and experimental mutation of BPSS2053, a GI gene, reduced microbial adherence to human epithelial cells is suggested.