R
Rajendra Joshi
Researcher at Centre for Development of Advanced Computing
Publications - 97
Citations - 2160
Rajendra Joshi is an academic researcher from Centre for Development of Advanced Computing. The author has contributed to research in topics: Gene & DNA. The author has an hindex of 18, co-authored 88 publications receiving 1845 citations. Previous affiliations of Rajendra Joshi include Savitribai Phule Pune University & Indian Institute of Remote Sensing.
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Journal ArticleDOI
A large-scale evaluation of computational protein function prediction
Predrag Radivojac,Wyatt T. Clark,Tal Ronnen Oron,Alexandra M. Schnoes,Tobias Wittkop,Artem Sokolov,Artem Sokolov,Kiley Graim,Christopher S. Funk,Karin Verspoor,Asa Ben-Hur,Gaurav Pandey,Gaurav Pandey,Jeffrey M. Yunes,Ameet Talwalkar,Susanna Repo,Susanna Repo,Michael L Souza,Damiano Piovesan,Rita Casadio,Zheng Wang,Jianlin Cheng,Hai Fang,Julian Gough,Patrik Koskinen,Petri Törönen,Jussi Nokso-Koivisto,Liisa Holm,Domenico Cozzetto,Daniel W. A. Buchan,Kevin Bryson,David T. Jones,Bhakti Limaye,Harshal Inamdar,Avik Datta,Sunitha K Manjari,Rajendra Joshi,Meghana Chitale,Daisuke Kihara,Andreas Martin Lisewski,Serkan Erdin,Eric Venner,Olivier Lichtarge,Robert Rentzsch,Haixuan Yang,Alfonso E. Romero,Prajwal Bhat,Alberto Paccanaro,Tobias Hamp,Rebecca Kaßner,Stefan Seemayer,Esmeralda Vicedo,Christian Schaefer,Dominik Achten,Florian Auer,Ariane Boehm,Tatjana Braun,Maximilian Hecht,Mark Heron,Peter Hönigschmid,Thomas A. Hopf,Stefanie Kaufmann,Michael Kiening,Denis Krompass,Cedric Landerer,Yannick Mahlich,Manfred Roos,Jari Björne,Tapio Salakoski,Andrew Wong,Hagit Shatkay,Hagit Shatkay,Fanny Gatzmann,Ingolf Sommer,Mark N. Wass,Michael J.E. Sternberg,Nives Škunca,Fran Supek,Matko Bošnjak,Panče Panov,Sašo Džeroski,Tomislav Šmuc,Yiannis A. I. Kourmpetis,Yiannis A. I. Kourmpetis,Aalt D. J. van Dijk,Cajo J. F. ter Braak,Yuanpeng Zhou,Qingtian Gong,Xinran Dong,Weidong Tian,Marco Falda,Paolo Fontana,Enrico Lavezzo,Barbara Di Camillo,Stefano Toppo,Liang Lan,Nemanja Djuric,Yuhong Guo,Slobodan Vucetic,Amos Marc Bairoch,Amos Marc Bairoch,Michal Linial,Patricia C. Babbitt,Steven E. Brenner,Christine A. Orengo,Burkhard Rost,Sean D. Mooney,Iddo Friedberg +107 more
TL;DR: Today's best protein function prediction algorithms substantially outperform widely used first-generation methods, with large gains on all types of targets, and there is considerable need for improvement of currently available tools.
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Mixed-Ligand Copper(II) Maltolate Complexes: Synthesis, Characterization, DNA Binding and Cleavage, and Cytotoxicity
Archika C. Barve,Avinash S. Kumbhar,Menakshi Bhat,Bimba N. Joshi,Ray J. Butcher,Uddhavesh B. Sonawane,Rajendra Joshi +6 more
TL;DR: The cytotoxicity of the complexes against HeLa (cervical) cancer cell lines shows that synergy between the metal and ligands results in a significant enhancement in the cell death with IC(50) of approximately 150-270 microg mL(-1).
Journal ArticleDOI
Synthesis, characterization, X-ray structure and DNA photocleavage by cis-dichloro bis(diimine) Co(III) complexes.
Smita Ghosh,Archika C. Barve,Anupa A. Kumbhar,Avinash S. Kumbhar,Vedavati G. Puranik,Prasanna A. Datar,Uddhavesh B. Sonawane,Rajendra Joshi +7 more
TL;DR: Molecular modeling studies show that the minimized structure of [Co(phendione)2Cl2]+, maintained the octahedral structure while binding to the N7 of guanines and the ligand fits into the major groove without disrupting the helical structure of the B-DNA.
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Ruthenium(II) complexes of bipyridine-glycoluril and their interactions with DNA.
Megha S. Deshpande,Anupa A. Kumbhar,Avinash S. Kumbhar,Manoj Kumbhakar,Haridas Pal,Uddhavesh B. Sonawane,Rajendra Joshi +6 more
TL;DR: Nine complexes with the peripheral polypyridyl ligands have the ability to form conjugates with DNA and show extensive DNA cleavage in the presence of light with a shift in mobility of form I of DNA probably due to the high molecular weight of DNA-complex conjugate.
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Genome Sequences of Salmonella enterica Serovar Typhimurium, Choleraesuis, Dublin, and Gallinarum Strains of Well- Defined Virulence in Food-Producing Animals
Emily J Richardson,Bhakti Limaye,Harshal Inamdar,Avik Datta,K. Sunitha Manjari,Gillian D. Pullinger,Nicholas R. Thomson,Rajendra Joshi,Michael Watson,Mark P. Stevens +9 more
TL;DR: The genomes of serovar Typhimurium, Choleraesuis, Dublin, and Gallinarum strains of defined virulence in each of three food-producing animal hosts provide valuable measures of intraserovar diversity and opportunities to formally link genotypes to phenotypes in target animals.