Robert Fagard

TL;DR: It is suggested that TGF-beta1-activated MyoFbs can be growth-arrested by two checkpoints, the G1/S checkpoint, which prevents cells from entering S-phase and the intra-S checkpoints, which is activated by encountering DNA damage during the S phase or by unrepaired damage that escapes the G 1/S checkpoints.

TL;DR: Use of Cornell voltage and Cornell product criteria for LVH predicted the risk of cardiovascular disease and stroke and the identification of ECG LVH proved to be important in very elderly hypertensive people.

TL;DR: In 66 patients examined twice on 10 mg lisinopril at a median interval of 32 days, the trough-to-peak ratios were characterized by large intraindividual variability, and by smoothing of the diurnal blood pressure profiles.

TL;DR: The study demonstrated moderate heritability for LV mass as well as the mitral annular Ea and Aa peaks, which support the ongoing research to map and detect genetic variants that contribute to the variation in LV mass and other LV structural and functional phenotypes.

TL;DR: The result suggests that the apparent effect on blood pressure is not the only cause of stroke risk reduction in hypertensive subjects submitted to an antihypertensive medicine, and that the mechanism of risk reduction obtained by blood pressure‐lowering pharmacological treatment remains unclear.