Robert Fagard

TL;DR: In this paper, the authors explored how in parallel-group trials interindividual variability, correction for placebo effects, and smoothing of blood pressure profiles can be handled in measuring the trough-to-peak ratio in 244 individuals with isolated systolic hypertension (≥60 years) enrolled in the placebo-controlled Systolic Hypertension in Europe Trial.

TL;DR: The plasma renin concentration of the same pre-extracted human plasma samples is measured by both a bioassay and a radioimmunoassay technique.

TL;DR: Monotherapy with nitrendipine or acebutolol offers an effective, safe first‐line antihypertensive treatment in blacks entered in this study; with the described dosages and therapeutic schedule, nitrendIPine was somewhat more effective than ace butolol.

TL;DR: Actuely administered felodipine was a potent dilator of systemic but not of pulmonary arterioles, it stimulated the sympathetic nervous system, and reduced left ventricular filling pressure.

TL;DR: The lower peak oxygen uptake of women results from both central and peripheral factors, which could result from their smaller muscle mass, lower capillary density, and lower oxidative potential.