R
Rolf Olsen
Researcher at University of California, San Diego
Publications - 7
Citations - 1610
Rolf Olsen is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Multiple sequence alignment & Genome. The author has an hindex of 6, co-authored 7 publications receiving 1544 citations. Previous affiliations of Rolf Olsen include Baylor College of Medicine.
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Journal ArticleDOI
The genome of the social amoeba Dictyostelium discoideum
Ludwig Eichinger,Justin A. Pachebat,Justin A. Pachebat,Gernot Glöckner,Marie-Adèle Rajandream,Richard Sucgang,Matthew Berriman,J. Song,Rolf Olsen,Karol Szafranski,Qikai Xu,Budi Tunggal,Sarah K. Kummerfeld,Martin Madera,Bernard Anri Konfortov,Francisco Rivero,Alan T. Bankier,Rüdiger Lehmann,N. Hamlin,Robert L. Davies,Pascale Gaudet,Petra Fey,Karen E Pilcher,Guokai Chen,David L. Saunders,Erica Sodergren,P. Davis,Arnaud Kerhornou,X. Nie,Neil Hall,Christophe Anjard,Lisa Hemphill,Nathalie Bason,Patrick Farbrother,Brian A. Desany,Eric M. Just,Takahiro Morio,René Rost,Carol Churcher,J. Cooper,Stephen F. Haydock,N. van Driessche,Ann Cronin,Ian Goodhead,Donna M. Muzny,T. Mourier,Arnab Pain,Mingyang Lu,D. Harper,R. Lindsay,Heidi Hauser,Kylie R. James,M. Quiles,M. Madan Babu,Tsuneyuki Saito,Carmen Buchrieser,A. Wardroper,A. Wardroper,Marius Felder,M. Thangavelu,D. Johnson,Andrew J Knights,H. Loulseged,Karen Mungall,Karen Oliver,Claire Price,Michael A. Quail,Hideko Urushihara,Judith Hernandez,Ester Rabbinowitsch,David Steffen,Mandy Sanders,Jun Ma,Yuji Kohara,Sarah Sharp,Mark Simmonds,S. Spiegler,Adrian Tivey,Sumio Sugano,Brian White,Danielle Walker,John Woodward,Thomas Winckler,Yoshiaki Tanaka,Gad Shaulsky,Michael Schleicher,George M. Weinstock,André Rosenthal,Edward C. Cox,Rex L. Chisholm,Richard A. Gibbs,William F. Loomis,Matthias Platzer,Robert R. Kay,Jeffrey G. Williams,Paul H. Dear,Angelika A. Noegel,Bart Barrell,Adam Kuspa +98 more
TL;DR: A proteome-based phylogeny shows that the amoebozoa diverged from the animal–fungal lineage after the plant–animal split, but Dictyostelium seems to have retained more of the diversity of the ancestral genome than have plants, animals or fungi.
Journal ArticleDOI
The estimation of statistical parameters for local alignment score distributions
TL;DR: This work describes a form of the recently described 'island' method in detail, and uses it to investigate the functional dependence of these parameters on finite-length edge effects.
Proceedings Article
Rapid Assessment of Extremal Statistics for Gapped Local Alignment
TL;DR: By identifying a complete set of linked clusters, "islands," this work devise a method which accurately predicts the extremal score statistics by using only one to a few pairwise alignments, and relies crucially on the link between the statistics of island scores and extremalscore statistics.
Journal ArticleDOI
Comparing the Dictyostelium and Entamoeba Genomes Reveals an Ancient Split in the Conosa Lineage
Jie Song,Qikai Xu,Rolf Olsen,Rolf Olsen,William F. Loomis,William F. Loomis,Gad Shaulsky,Adam Kuspa,Richard Sucgang +8 more
TL;DR: It is found that only 42 gene families are distinct to the amoeba lineage; among these are a large number of proteins that contain repeats of the FNIP domain, and a putative transcription factor essential for proper cell type differentiation in D. discoideum.
Proceedings ArticleDOI
Optimizing Smith-Waterman alignments.
TL;DR: A new fidelity measure is introduced and shown to capture the significance of the local alignment, i.e., the extent to which the correlated subsequences are correctly identified.