K
Karol Szafranski
Researcher at National Institutes of Health
Publications - 77
Citations - 4089
Karol Szafranski is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & Alternative splicing. The author has an hindex of 28, co-authored 74 publications receiving 3672 citations. Previous affiliations of Karol Szafranski include Schiller International University & Analysis Group.
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Journal ArticleDOI
The genome of the social amoeba Dictyostelium discoideum
Ludwig Eichinger,Justin A. Pachebat,Justin A. Pachebat,Gernot Glöckner,Marie-Adèle Rajandream,Richard Sucgang,Matthew Berriman,J. Song,Rolf Olsen,Karol Szafranski,Qikai Xu,Budi Tunggal,Sarah K. Kummerfeld,Martin Madera,Bernard Anri Konfortov,Francisco Rivero,Alan T. Bankier,Rüdiger Lehmann,N. Hamlin,Robert L. Davies,Pascale Gaudet,Petra Fey,Karen E Pilcher,Guokai Chen,David L. Saunders,Erica Sodergren,P. Davis,Arnaud Kerhornou,X. Nie,Neil Hall,Christophe Anjard,Lisa Hemphill,Nathalie Bason,Patrick Farbrother,Brian A. Desany,Eric M. Just,Takahiro Morio,René Rost,Carol Churcher,J. Cooper,Stephen F. Haydock,N. van Driessche,Ann Cronin,Ian Goodhead,Donna M. Muzny,T. Mourier,Arnab Pain,Mingyang Lu,D. Harper,R. Lindsay,Heidi Hauser,Kylie R. James,M. Quiles,M. Madan Babu,Tsuneyuki Saito,Carmen Buchrieser,A. Wardroper,A. Wardroper,Marius Felder,M. Thangavelu,D. Johnson,Andrew J Knights,H. Loulseged,Karen Mungall,Karen Oliver,Claire Price,Michael A. Quail,Hideko Urushihara,Judith Hernandez,Ester Rabbinowitsch,David Steffen,Mandy Sanders,Jun Ma,Yuji Kohara,Sarah Sharp,Mark Simmonds,S. Spiegler,Adrian Tivey,Sumio Sugano,Brian White,Danielle Walker,John Woodward,Thomas Winckler,Yoshiaki Tanaka,Gad Shaulsky,Michael Schleicher,George M. Weinstock,André Rosenthal,Edward C. Cox,Rex L. Chisholm,Richard A. Gibbs,William F. Loomis,Matthias Platzer,Robert R. Kay,Jeffrey G. Williams,Paul H. Dear,Angelika A. Noegel,Bart Barrell,Adam Kuspa +98 more
TL;DR: A proteome-based phylogeny shows that the amoebozoa diverged from the animal–fungal lineage after the plant–animal split, but Dictyostelium seems to have retained more of the diversity of the ancestral genome than have plants, animals or fungi.
Journal ArticleDOI
Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish.
Kathrin Reichwald,Andreas Petzold,Philipp Koch,Bryan R. Downie,Nils Hartmann,Stefan Pietsch,Mario Baumgart,Domitille Chalopin,Marius Felder,Martin Bens,Arne Sahm,Karol Szafranski,Stefan Taudien,Marco Groth,Ivan Arisi,Anja Weise,Samarth Bhatt,Virag Sharma,Johann M. Kraus,Florian Schmid,Steffen Priebe,Thomas Liehr,Matthias Görlach,Manuel E Than,Michael Hiller,Hans A. Kestler,Hans A. Kestler,Hans A. Kestler,Jean-Nicolas Volff,Manfred Schartl,Alessandro Cellerino,Christoph Englert,Christoph Englert,Matthias Platzer +33 more
TL;DR: The killifish Nothobranchius furzeri is the shortest-lived vertebrate that can be bred in the laboratory and an intra-species Y chromosome polymorphism representing-in real time-different stages of sex chromosome formation that display features of early mammalian XY evolution "in action" is uncovered.
Journal ArticleDOI
Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting
Claudia Fritsch,A Herrmann,Michael Nothnagel,Karol Szafranski,Klaus Huse,Frank Schumann,Stefan Schreiber,Matthias Platzer,Michael Krawczak,Jochen Hampe,Mario Brosch +10 more
TL;DR: A transcriptome-wide map of novel candidate TISs derived as part of the study will shed further light on the way in which human proteome diversity is influenced by alternative translation initiation and regulation.
Journal ArticleDOI
Sequence and analysis of chromosome 2 of Dictyostelium discoideum
Gernot Glöckner,Ludwig Eichinger,Karol Szafranski,Justin A. Pachebat,Alan T. Bankier,Paul H. Dear,Rüdiger Lehmann,Cornelia Baumgart,Genís Parra,Josep F. Abril,Roderic Guigó,Kai Kumpf,Budi Tunggal,Edward C. Cox,Michael A. Quail,Matthias Platzer,André Rosenthal,Angelika A. Noegel,Bart Barrell,Marie-Adèle Rajandream,Jeffrey G. Williams,Robert R. Kay,Adam Kuspa,Richard A. Gibbs,Richard Sucgang,Donna M. Muzny,Brian A. Desany,Kathy Zeng,Baoli Zhu,Pieter J. de Jong,Theodor Dingermann,Günther Gerisch,Peter Philippsen,Michael Schleicher,Stephan C. Schuster,Thomas Winckler +35 more
TL;DR: A significant number of the genes show higher similarities to genes of vertebrates than to those of other fully sequenced eukaryotes, which strengthens the view that the evolutionary position of D. discoideum is located before the branching of metazoa and fungi but after the divergence of the plant kingdom.
Journal ArticleDOI
Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi
Anke Burmester,Anke Burmester,Ekaterina Shelest,Gernot Glöckner,Christoph Heddergott,Christoph Heddergott,Susann Schindler,Susann Schindler,Peter Staib,Andrew J. Heidel,Marius Felder,Andreas Petzold,Karol Szafranski,Marc Feuermann,Ivo Pedruzzi,Steffen Priebe,Marco Groth,Robert Winkler,Robert Winkler,Wenjun Li,Olaf Kniemeyer,Volker Schroeckh,Christian Hertweck,Christian Hertweck,Bernhard Hube,Bernhard Hube,Theodore C. White,Matthias Platzer,Reinhard Guthke,Joseph Heitman,Johannes Wöstemeyer,Peter F. Zipfel,Peter F. Zipfel,Michel Monod,Axel A. Brakhage,Axel A. Brakhage +35 more
TL;DR: The first genome sequences of two closely phylogenetically related dermatophytes, Arthroderma benhamiae and Trichophyton verrucosum, both of which induce highly inflammatory infections in humans, are reported, enlighten the genetic basis of fundamental and putatively virulence-related traits of dermatophyts, advancing future research on these medically important pathogens.