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Nikhat Zafar
Researcher at J. Craig Venter Institute
Publications - 27
Citations - 8091
Nikhat Zafar is an academic researcher from J. Craig Venter Institute. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 22, co-authored 27 publications receiving 7335 citations. Previous affiliations of Nikhat Zafar include George Mason University & University of Maryland, Baltimore.
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Journal ArticleDOI
Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial “pan-genome”
Hervé Tettelin,Vega Masignani,Michael J. Cieslewicz,Claudio Donati,Duccio Medini,Naomi L. Ward,Samuel V. Angiuoli,Jonathan Crabtree,Amanda L. Jones,A. Scott Durkin,Robert T. DeBoy,Tanja M. Davidsen,Marirosa Mora,Maria Scarselli,Immaculada Margarit Y Ros,Jeremy Peterson,Christopher R. Hauser,Jaideep P. Sundaram,William C. Nelson,Ramana Madupu,Lauren M. Brinkac,Robert J. Dodson,M. J. Rosovitz,Steven A. Sullivan,Sean C. Daugherty,Daniel H. Haft,Jeremy D. Selengut,Michelle L. Gwinn,Liwei Zhou,Nikhat Zafar,Hoda Khouri,Diana Radune,George Dimitrov,Kisha Watkins,Kevin J. B. O'Connor,Shannon Smith,Teresa Utterback,Owen White,Craig E. Rubens,Guido Grandi,Lawrence C. Madoff,Dennis L. Kasper,John L. Telford,Michael R. Wessels,Rino Rappuoli,Claire M. Fraser +45 more
TL;DR: The genomic sequence of six strains representing the five major disease-causing serotypes of Streptococcus agalactiae, the main cause of neonatal infection in humans, was generated and Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactic pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes.
Journal ArticleDOI
The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000
C. Robin Buell,Vinita Joardar,Magdalen Lindeberg,Jeremy D. Selengut,Ian T. Paulsen,Michelle L. Gwinn,Robert J. Dodson,Robert T. DeBoy,A. Scott Durkin,James F. Kolonay,Ramana Madupu,Sean C. Daugherty,Lauren M. Brinkac,Maureen J. Beanan,Daniel H. Haft,William C. Nelson,Tanja M. Davidsen,Nikhat Zafar,Liwei Zhou,Jia Liu,Qiaoping Yuan,Hoda Khouri,Nadia Fedorova,Bao Tran,Daniel A. Russell,Kristi Berry,Teresa Utterback,Susan Van Aken,Tamara Feldblyum,Mark D'Ascenzo,Wen Ling Deng,Adela R. Ramos,James R. Alfano,Samuel W. Cartinhour,Arun K. Chatterjee,Terrence P. Delaney,Sondra G. Lazarowitz,Gregory B. Martin,David J. Schneider,Xiaoyan Tang,Carol L. Bender,Owen White,Claire M. Fraser,Alan Collmer +43 more
TL;DR: The complete genome sequence of the model bacterial pathogen Pseudomonas syringae pathovar tomato DC3000 (DC3000), which is pathogenic on tomato and Arabidopsis thaliana, is reported and 1,159 genes unique to DC3000 are revealed, of which 811 lack a known function.
Journal ArticleDOI
Three Genomes from the Phylum Acidobacteria Provide Insight into the Lifestyles of These Microorganisms in Soils
Naomi L. Ward,Jean F. Challacombe,Jean F. Challacombe,Peter H. Janssen,Peter H. Janssen,Bernard Henrissat,Pedro M. Coutinho,Martin Wu,Gary Xie,Gary Xie,Daniel H. Haft,Michelle Sait,Jonathan H. Badger,Ravi D. Barabote,Ravi D. Barabote,Brent Bradley,Thomas Brettin,Thomas Brettin,Lauren M. Brinkac,David Bruce,David Bruce,Todd Creasy,Sean C. Daugherty,Tanja M. Davidsen,Robert T. DeBoy,J. Chris Detter,J. Chris Detter,Robert J. Dodson,A. Scott Durkin,Anuradha Ganapathy,Michelle Gwinn-Giglio,Cliff Han,Cliff Han,Hoda Khouri,Hajnalka Kiss,Hajnalka Kiss,Sagar Kothari,Ramana Madupu,Karen E. Nelson,William C. Nelson,Ian T. Paulsen,Kevin Penn,Qinghu Ren,M. J. Rosovitz,Jeremy D. Selengut,Susmita Shrivastava,Steven A. Sullivan,Roxanne Tapia,Roxanne Tapia,L. Sue Thompson,L. Sue Thompson,Kisha Watkins,Qi Yang,Chunhui Yu,Nikhat Zafar,Liwei Zhou,Cheryl R. Kuske +56 more
TL;DR: Combining the genomic evidence with available culture traits, it is postulate that cells of these isolates are long-lived, divide slowly, exhibit slow metabolic rates under low-nutrient conditions, and are well equipped to tolerate fluctuations in soil hydration.
Journal ArticleDOI
Genome of Geobacter sulfurreducens: Metal Reduction in Subsurface Environments
Barbara A. Methé,Karen E. Nelson,Jonathan A. Eisen,Ian T. Paulsen,William C. Nelson,John F. Heidelberg,Dongying Wu,Martin Wu,Naomi L. Ward,Maureen J. Beanan,Robert J. Dodson,R. Madupu,Lauren M. Brinkac,Sean C. Daugherty,Robert T. DeBoy,Anthony S. Durkin,Michelle L. Gwinn,James F. Kolonay,Steven A. Sullivan,Daniel H. Haft,Jeremy D. Selengut,Tanja M. Davidsen,Nikhat Zafar,Owen White,Bao Tran,Claudia M. Romero,Heather Forberger,J. Weidman,H. Khouri,Tamara Feldblyum,T. Utterback,S. van Aken,Derek R. Lovley,Claire M. Fraser +33 more
TL;DR: The complete genome sequence of Geobacter sulfurreducens, a δ-proteobacterium, reveals unsuspected capabilities, including evidence of aerobic metabolism, one-carbon and complex carbon metabolism, motility, and chemotactic behavior, which suggest the organism has the potential for use in bioremediation of radioactive metals and in the generation of electricity.
Journal ArticleDOI
The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough
John F. Heidelberg,Rekha Seshadri,Shelley A. Haveman,Christopher L. Hemme,Ian T. Paulsen,James F. Kolonay,Jonathan A. Eisen,Naomi L. Ward,Barbara A. Methé,Lauren M. Brinkac,Sean C. Daugherty,Robert T. DeBoy,Robert J. Dodson,A. Scott Durkin,Ramana Madupu,William C. Nelson,Steven A. Sullivan,Derrick E. Fouts,Daniel H. Haft,Jeremy D. Selengut,Jeremy Peterson,Tanja M. Davidsen,Nikhat Zafar,Liwei Zhou,Diana Radune,George Dimitrov,Mark Hance,Kevin Tran,Hoda Khouri,John Gill,T. Utterback,Tamara Feldblyum,Judy D. Wall,Gerrit Voordouw,Claire M. Fraser +34 more
TL;DR: The relative arrangement of genes encoding enzymes for energy transduction, together with inferred cellular location of the enzymes, provides a basis for proposing an expansion to the 'hydrogen-cycling' model for increasing energy efficiency in this bacterium.