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David W. Hedley

Researcher at Princess Margaret Cancer Centre

Publications -  328
Citations -  23891

David W. Hedley is an academic researcher from Princess Margaret Cancer Centre. The author has contributed to research in topics: Cancer & Pancreatic cancer. The author has an hindex of 75, co-authored 321 publications receiving 21469 citations. Previous affiliations of David W. Hedley include Lunenfeld-Tanenbaum Research Institute & University of Sydney.

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Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry

TL;DR: There was a good correlation between the DNA histograms produced using this method and those obtained using unfixed tissue from the same tumor stained with ethidium bromide plus mithramycin.
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Pan-cancer analysis of whole genomes

Peter J. Campbell, +1332 more
- 06 Feb 2020 - 
TL;DR: The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.
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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Andrea Cossarizza, +462 more
TL;DR: These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community providing the theory and key practical aspects offlow cytometry enabling immunologists to avoid the common errors that often undermine immunological data.
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Guidelines for the use of flow cytometry and cell sorting in immunological studies

Andrea Cossarizza, +246 more
TL;DR: A rapid search in PubMed shows that using "flow cytometry immunology" as a search term yields more than 68 000 articles, the first of which is not about lymphocytes as mentioned in this paper.
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The distribution of the anticancer drug Doxorubicin in relation to blood vessels in solid tumors.

TL;DR: Limited distribution of doxorubicin in solid tumors is an important and neglected cause of clinical resistance that is amenable to modification and can be adapted to studying the distribution of other drugs within solid tumors and the effect of strategies to modify their distribution.