S
Sandra Koch
Researcher at University of Mainz
Publications - 35
Citations - 1357
Sandra Koch is an academic researcher from University of Mainz. The author has contributed to research in topics: Hepatocellular carcinoma & Sorafenib. The author has an hindex of 13, co-authored 34 publications receiving 719 citations.
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Journal ArticleDOI
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
Dominik Pfister,Dominik Pfister,Nicolás Gonzalo Núñez,Roser Pinyol,Olivier Govaere,Matthias Pinter,Marta Szydlowska,Revant Gupta,Mengjie Qiu,Aleksandra Deczkowska,Assaf Weiner,Florian Müller,Ankit Sinha,Ankit Sinha,Ekaterina Friebel,Thomas Engleitner,Thomas Engleitner,Daniela Lenggenhager,Anja Moncsek,Danijela Heide,Kristin Stirm,Jan Kosla,Eleni Kotsiliti,Valentina Leone,Michael Dudek,Suhail Yousuf,Donato Inverso,Donato Inverso,Indrabahadur Singh,Ana Teijeiro,Florian Castet,Carla Montironi,Philipp K. Haber,Dina Tiniakos,Dina Tiniakos,Pierre Bedossa,Simon Cockell,Ramy Younes,Ramy Younes,Michele Vacca,Fabio Marra,Jörn M. Schattenberg,Michael Allison,Elisabetta Bugianesi,Vlad Ratziu,Tiziana Pressiani,Antonio D'Alessio,Nicola Personeni,Lorenza Rimassa,Ann K. Daly,Bernhard Scheiner,Katharina Pomej,Martha M. Kirstein,Arndt Vogel,Markus Peck-Radosavljevic,F. Hucke,Fabian Finkelmeier,Oliver Waidmann,Jörg Trojan,Kornelius Schulze,Henning Wege,Sandra Koch,Arndt Weinmann,Marco Bueter,Fabian Rössler,Alexander Siebenhüner,Sara De Dosso,Jan-Philipp Mallm,Viktor Umansky,Viktor Umansky,Manfred Jugold,Tom Luedde,Andrea Schietinger,Andrea Schietinger,Peter Schirmacher,Brinda Emu,Hellmut G. Augustin,Hellmut G. Augustin,Adrian T. Billeter,Beat P. Müller-Stich,Hiroto Kikuchi,Dan G. Duda,Fabian Kütting,Dirk Waldschmidt,Matthias P. Ebert,Nuh N. Rahbari,Henrik E. Mei,Axel Schulz,Marc Ringelhan,Nisar P. Malek,Stephan Spahn,Michael Bitzer,Marina Ruiz de Galarreta,Amaia Lujambio,Jean-François Dufour,Thomas U. Marron,Thomas U. Marron,Ahmed Kaseb,Masatoshi Kudo,Yi Hsiang Huang,Yi Hsiang Huang,Nabil Djouder,Katharina Wolter,Lars Zender,Lars Zender,Parice N. Marche,Parice N. Marche,Thomas Decaens,Thomas Decaens,David J. Pinato,Roland Rad,Roland Rad,Joachim C. Mertens,Achim Weber,Kristian Unger,Felix Meissner,Susanne Roth,Zuzana Macek Jilkova,Zuzana Macek Jilkova,Zuzana Macek Jilkova,Manfred Claassen,Quentin M. Anstee,Ido Amit,Percy A. Knolle,Burkhard Becher,Josep M. Llovet,Josep M. Llovet,Josep M. Llovet,Mathias Heikenwalder +128 more
TL;DR: The progressive accumulation of exhausted, unconventionally activated CD8+PD1+ T cells in NASH-affected livers provides a rationale for stratification of patients with HCC according to underlying aetiology in studies of immunotherapy as a primary or adjuvant treatment.
Journal ArticleDOI
Programmed cell death protein-1 (PD-1)-targeted immunotherapy in advanced hepatocellular carcinoma: efficacy and safety data from an international multicentre real-world cohort
Bernhard Scheiner,Martha M. Kirstein,F. Hucke,Fabian Finkelmeier,Kornelius Schulze,Johann von Felden,Sandra Koch,Philipp Schwabl,Jan B. Hinrichs,Fredrik Waneck,Oliver Waidmann,Thomas Reiberger,Christian Müller,Wolfgang Sieghart,Michael Trauner,Arndt Weinmann,Henning Wege,Jörg Trojan,Markus Peck-Radosavljevic,Arndt Vogel,Matthias Pinter +20 more
TL;DR: Programmed cell death protein‐1‐targeted immunotherapy has shown promising results in phase II studies of hepatocellular carcinoma.
Journal ArticleDOI
Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma
Arndt Weinmann,Y Alt,Sandra Koch,Carina Nelles,Christoph Düber,Hauke Lang,Gerd Otto,Tim Zimmermann,Jens U. Marquardt,Peter R. Galle,Marcus A. Wörns,Jörn M. Schattenberg +11 more
TL;DR: Despite retained liver function, patients with NASH-associated HCC showed a decreased overall survival and it will be necessary to improve screening and surveillance strategies to identify HCC in NASH early and improve survival.
Journal ArticleDOI
Trends in epidemiology, treatment, and survival of hepatocellular carcinoma patients between 1998 and 2009: an analysis of 1066 cases of a German HCC Registry.
Arndt Weinmann,Sandra Koch,Ina M. Niederle,Henning Schulze-Bergkamen,Jochem König,Maria Hoppe-Lotichius,Torsten Hansen,Michael B. Pitton,Christoph Düber,Gerd Otto,Marcus Schuchmann,Peter R. Galle,Marcus A. Wörns +12 more
TL;DR: Analysis of clinical presentation, course of disease, and management of patients with hepatocellular carcinoma in a German referral center between 1998 and 2009 found no improvement of OS was observed when comparing time periods.
Journal ArticleDOI
Metabolic syndrome and its association with fatty liver disease after orthotopic liver transplantation.
Martin F. Sprinzl,Arndt Weinmann,Nikola Lohse,Hanna Tönissen,Sandra Koch,Jörn M. Schattenberg,Maria Hoppe-Lotichius,Tim Zimmermann,Peter R. Galle,Torsten Hansen,Gerd Otto,Marcus Schuchmann +11 more
TL;DR: Low threshold HbA1c as a novel risk factor for MetS after OLT was identified and a link of MetS with NAFLD in transplant organs was described and indicated that steroid treatment is associated with MetS rates afterOLT.