R
Revant Gupta
Researcher at University of Tübingen
Publications - 7
Citations - 567
Revant Gupta is an academic researcher from University of Tübingen. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 2, co-authored 4 publications receiving 89 citations. Previous affiliations of Revant Gupta include ETH Zurich & Swiss Institute of Bioinformatics.
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Journal ArticleDOI
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
Dominik Pfister,Dominik Pfister,Nicolás Gonzalo Núñez,Roser Pinyol,Olivier Govaere,Matthias Pinter,Marta Szydlowska,Revant Gupta,Mengjie Qiu,Aleksandra Deczkowska,Assaf Weiner,Florian Müller,Ankit Sinha,Ankit Sinha,Ekaterina Friebel,Thomas Engleitner,Thomas Engleitner,Daniela Lenggenhager,Anja Moncsek,Danijela Heide,Kristin Stirm,Jan Kosla,Eleni Kotsiliti,Valentina Leone,Michael Dudek,Suhail Yousuf,Donato Inverso,Donato Inverso,Indrabahadur Singh,Ana Teijeiro,Florian Castet,Carla Montironi,Philipp K. Haber,Dina Tiniakos,Dina Tiniakos,Pierre Bedossa,Simon Cockell,Ramy Younes,Ramy Younes,Michele Vacca,Fabio Marra,Jörn M. Schattenberg,Michael Allison,Elisabetta Bugianesi,Vlad Ratziu,Tiziana Pressiani,Antonio D'Alessio,Nicola Personeni,Lorenza Rimassa,Ann K. Daly,Bernhard Scheiner,Katharina Pomej,Martha M. Kirstein,Arndt Vogel,Markus Peck-Radosavljevic,F. Hucke,Fabian Finkelmeier,Oliver Waidmann,Jörg Trojan,Kornelius Schulze,Henning Wege,Sandra Koch,Arndt Weinmann,Marco Bueter,Fabian Rössler,Alexander Siebenhüner,Sara De Dosso,Jan-Philipp Mallm,Viktor Umansky,Viktor Umansky,Manfred Jugold,Tom Luedde,Andrea Schietinger,Andrea Schietinger,Peter Schirmacher,Brinda Emu,Hellmut G. Augustin,Hellmut G. Augustin,Adrian T. Billeter,Beat P. Müller-Stich,Hiroto Kikuchi,Dan G. Duda,Fabian Kütting,Dirk Waldschmidt,Matthias P. Ebert,Nuh N. Rahbari,Henrik E. Mei,Axel Schulz,Marc Ringelhan,Nisar P. Malek,Stephan Spahn,Michael Bitzer,Marina Ruiz de Galarreta,Amaia Lujambio,Jean-François Dufour,Thomas U. Marron,Thomas U. Marron,Ahmed Kaseb,Masatoshi Kudo,Yi Hsiang Huang,Yi Hsiang Huang,Nabil Djouder,Katharina Wolter,Lars Zender,Lars Zender,Parice N. Marche,Parice N. Marche,Thomas Decaens,Thomas Decaens,David J. Pinato,Roland Rad,Roland Rad,Joachim C. Mertens,Achim Weber,Kristian Unger,Felix Meissner,Susanne Roth,Zuzana Macek Jilkova,Zuzana Macek Jilkova,Zuzana Macek Jilkova,Manfred Claassen,Quentin M. Anstee,Ido Amit,Percy A. Knolle,Burkhard Becher,Josep M. Llovet,Josep M. Llovet,Josep M. Llovet,Mathias Heikenwalder +128 more
TL;DR: The progressive accumulation of exhausted, unconventionally activated CD8+PD1+ T cells in NASH-affected livers provides a rationale for stratification of patients with HCC according to underlying aetiology in studies of immunotherapy as a primary or adjuvant treatment.
Journal ArticleDOI
Deterministic scRNA-seq captures variation in intestinal crypt and organoid composition
Johannes Bues,Marjan Biočanin,Joern Pezoldt,Riccardo Dainese,Antonius Chrisnandy,Saba Rezakhani,Wouter Saelens,Vincent Gardeux,Revant Gupta,Rita Sarkis,Julie Russeil,Yvan Saeys,Esther Amstad,Manfred Claassen,Matthias P. Lutolf,Bart Deplancke +15 more
TL;DR: DisCo as mentioned in this paper is a deterministic droplet microfluidics tool for single-cell analysis on low cell input samples, which is demonstrated to profile individual intestinal organoids and in vivo-derived small tissues.
Journal ArticleDOI
psupertime: supervised pseudotime analysis for time-series single-cell RNA-seq data
TL;DR:
Posted ContentDOI
Fate trajectories of CD8+ T cells in chronic LCMV infection
TL;DR: In this article, a comprehensive scRNAseq time-series analysis from beginning of infection to established exhaustion in CD8+ T cells is presented, which is characterized by impaired effector functions and expression of co-inhibitory receptors as response to continuous TCR stimulation.
Posted ContentDOI
Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools
Johannes Bues,Johannes Bues,Marjan Biočanin,Marjan Biočanin,Joern Pezoldt,Joern Pezoldt,Riccardo Dainese,Riccardo Dainese,Antonius Chrisnandy,Saba Rezakhani,Wouter Saelens,Revant Gupta,Revant Gupta,Julie Russeil,Julie Russeil,Yvan Saeys,Esther Amstad,Manfred Claassen,Manfred Claassen,Matthias P. Lutolf,Bart Deplancke,Bart Deplancke +21 more
TL;DR: A deterministic, mRNA-capture bead and cell co-encapsulation dropleting system, DisCo, that enables precise particle and cell positioning and droplet sorting control through combined machine-vision and multilayer microfluidics and demonstrates the unique power of DisCo in providing high-resolution snapshots of cellular heterogeneity among small, individual tissues.