S
Sara Lacerda
Researcher at University of Orléans
Publications - 44
Citations - 640
Sara Lacerda is an academic researcher from University of Orléans. The author has contributed to research in topics: Elastin & Chemistry. The author has an hindex of 14, co-authored 37 publications receiving 509 citations. Previous affiliations of Sara Lacerda include Centre national de la recherche scientifique & St Thomas' Hospital.
Papers
More filters
Journal ArticleDOI
X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations
Slavka Kascakova,Alexandre Giuliani,Sara Lacerda,Agnès Pallier,Pascal Mercère,Éva Tóth,Matthieu Réfrégiers +6 more
TL;DR: In this paper, the proposed nanolipoparticles, which contain both lanthanides and photosensitizer molecules, offer new opportunities in therapy and diagnosis, by transferring visible energy to a photo-sensor and triggering photodynamic therapy (PDT) even in deep tumors.
Journal ArticleDOI
13- and 14-membered macrocyclic ligands containing methylcarboxylate or methylphosphonate pendant arms: Chemical and biological evaluation of their 153Sm and 166Ho complexes as potential agents for therapy or bone pain palliation
Fernanda Marques,Lurdes Gano,M. Paula C. Campello,Sara Lacerda,Isabel Santos,Luís M. P. Lima,Judite Costa,Patricia Antunes,Rita Delgado +8 more
TL;DR: Biodistribution studies in mice demonstrated that (153)Sm/(166)Ho-trita complexes have a fast tissue clearance with more than 95% of the injected activity excreted after 2 h, value that is comparable to the corresponding dota complexes, in contrast, the ( 153)Sm-teta complex has a significantly lower total excretion.
Journal ArticleDOI
In Vivo Assessment of Aortic Aneurysm Wall Integrity Using Elastin-Specific Molecular Magnetic Resonance Imaging
René M. Botnar,Andrea J. Wiethoff,Ullrich Ebersberger,Sara Lacerda,Ulrike Blume,Alice Warley,Christian Jansen,David C. Onthank,Richard R. Cesati,Reza Razavi,Michael S. Marber,Bernd Hamm,Tobias Schaeffter,Simon P. Robinson,Marcus R. Makowski +14 more
TL;DR: ESMA-MRI offers potential for the noninvasive detection of the aortic rupture site prior to dilation of theAorta and the subsequent in vivo monitoring of compensatory repair processes during the progression of AAAs.
Journal ArticleDOI
Unprecedented Kinetic Inertness for a Mn 2+ ‐Bispidine Chelate: A Novel Structural Entry for Mn 2+ ‐Based Imaging Agents
Daouda Ndiaye,Maryame Sy,Agnès Pallier,Sandra Même,Isidro de Silva,Sara Lacerda,Aline Nonat,Loïc J. Charbonnière,Éva Tóth +8 more
TL;DR: In vivo MRI experiments in mice and determination of the tissue Mn content evidence rapid renal clearance of MnL 1 and the strongly preorganized structure of the 2,4-pyridyl-disubstituted bispidol ligand L 1 endows its Mn 2+ complex with exceptional kinetic inertness.
Journal ArticleDOI
Lanthanide(III) complexes of 4,10-bis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane-1,7-diacetic acid (trans-H6do2a2p) in solution and in the solid state: structural studies along the series.
M. Paula C. Campello,Sara Lacerda,Isabel Santos,Giovannia A. L. Pereira,Giovannia A. L. Pereira,Carlos F. G. C. Geraldes,Jan Kotek,Petr Hermann,Jakub Vaněk,Přemysl Lubal,Vojtěch Kubíček,Vojtěch Kubíček,Éva Tóth,Isabel Santos +13 more
TL;DR: In this paper, the stability constants of the divalent and trivalent metal-ion complexes are between the corresponding values of H(4)dota and H(8)dotp complexes, as a consequence of the ligand basicity.