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Serge Gauthier
Researcher at McGill University
Publications - 715
Citations - 61038
Serge Gauthier is an academic researcher from McGill University. The author has contributed to research in topics: Dementia & Disease. The author has an hindex of 93, co-authored 637 publications receiving 52775 citations. Previous affiliations of Serge Gauthier include Hamamatsu University School of Medicine & La Salle University.
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The Consortium for the early identification of Alzheimer's disease-Quebec (CIMA-Q).
Sylvie Belleville,Andréa C. LeBlanc,Marie-Jeanne Kergoat,Frédéric Calon,Pierrette Gaudreau,Sébastien S. Hébert,Carol Hudon,Nicole Leclerc,Naguib Mechawar,Simon Duchesne,Serge Gauthier,Pierre Bellec,Christian Bocti,Howard Chertkow,Louis Collins,Stephen C. Cunnane,Carol Hudon Marie-Jeanne-Kergoat,Natalie Philips,Jean-Paul Soucy,Thien Thanh Dang Vu,Louis Verret,Juan Manuel Villalpando +21 more
TL;DR: The Consortium for the early identification of Alzheimer's disease–Quebec (CIMA‐Q) created a research infrastructure to recruit, characterize, and track disease progression in individuals at risk of dementia.
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Synthesis and Comparison of the Meta-Analyses Evaluating the Efficacy of Memantine in Moderate to Severe Stages of Alzheimer’s Disease
TL;DR: Overall, results from individual clinical trials and from meta-analyses demonstrate that memantine represents a valuable treatment option in AD.
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Use of biomarkers in clinical trials of Alzheimer disease: from concept to application.
TL;DR: Biomarkers are biochemical and anatomical variables that measure AD-related pathologic features in vivo that play an important role in population enrichment by refining selection criteria, stratifying populations, and increasing the statistical power of trials.
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Trajectories of decline on instrumental activities of daily living prior to dementia in persons with mild cognitive impairment.
Simon Cloutier,Howard Chertkow,Marie-Jeanne Kergoat,Isabelle Gélinas,Serge Gauthier,Sylvie Belleville +5 more
TL;DR: The main objective was to determine the trajectory of instrumental activities of daily living decline in persons with mild cognitive impairment (MCI) who progressed towards dementia relative to persons with MCI who remained stable.
Journal ArticleDOI
Amyloid processing in COVID‐19‐associated neurological syndromes
Oliver J. Ziff,Nicholas J. Ashton,Puja Mehta,Rachel Brown,Dilan Athauda,Judith Heaney,Amanda Heslegrave,Andrea Lessa Benedet,Kaj Blennow,Anna M. Checkley,Catherine F Houlihan,Serge Gauthier,Pedro Rosa-Neto,Nick C. Fox,Jonathan M. Schott,Henrik Zetterberg,Laura A Benjamin,Ross W. Paterson +17 more
TL;DR: Altered amyloid processing was linked to neuronal injury and neuroinflammation but reduced astrocyte activation and a sensitivity analysis of COVID‐19‐associated GBS revealed a non‐significant trend toward greater impairment of amyloids processing in CO VID‐19 central than peripheral neurological syndromes.