S
Serge Gauthier
Researcher at McGill University
Publications - 715
Citations - 61038
Serge Gauthier is an academic researcher from McGill University. The author has contributed to research in topics: Dementia & Disease. The author has an hindex of 93, co-authored 637 publications receiving 52775 citations. Previous affiliations of Serge Gauthier include Hamamatsu University School of Medicine & La Salle University.
Papers
More filters
Journal ArticleDOI
EXACT: rivastigmine improves the high prevalence of attention deficits and mood and behaviour symptoms in Alzheimer's disease
TL;DR: The majority of patients treated with rivastigmine experienced improvements in attention, anxiety, apathy and agitation, and these real‐life findings further demonstrate the proven efficacy of rivASTigmine in patients with mild‐to‐moderate AD.
Journal ArticleDOI
Open science datasets from PREVENT-AD, a longitudinal cohort of pre-symptomatic Alzheimer's disease.
Jennifer Tremblay-Mercier,Cécile Madjar,Samir Das,Alexa Pichet Binette,Stephanie O.M. Dyke,Pierre Etienne,Marie-Elyse Lafaille-Magnan,Jordana Remz,Pierre Bellec,D. Louis Collins,M. Natasha Rajah,Véronique D. Bohbot,Jeannie Marie S. Leoutsakos,Yasser Iturria-Medina,Justin Kat,Richard D. Hoge,Serge Gauthier,Christine L. Tardif,M. Mallar Chakravarty,Jean-Baptiste Poline,Pedro Rosa-Neto,Alan C. Evans,Sylvia Villeneuve,Judes Poirier,John C.S. Breitner +24 more
TL;DR: The PREVENT-AD dataset as discussed by the authors is an open science dataset from the Canadian Open Neuroscience Platform, which contains up to five years of longitudinal imaging data, cerebral fluid biochemistry, neurosensory capacities, cognitive, genetic, and medical information, and most of the other information, sensitive by nature, is accessible by qualified researchers at https://registeredpreventad.loris.ca.
Journal ArticleDOI
Topographic Distribution of Amyloid-β, Tau, and Atrophy in Patients With Behavioral/Dysexecutive Alzheimer Disease
Joseph Therriault,Tharick A. Pascoal,Melissa Savard,Andrea Lessa Benedet,Mira Chamoun,Cecile Tissot,Firoza Z. Lussier,Min Su Kang,Emilie Thomas,Tatsuhiro Terada,Soham Rej,Gassan Massarweh,Ziad S. Nasreddine,Paolo Vitali,Jean-Paul Soucy,Paramita Saha-Chaudhuri,Serge Gauthier,Pedro Rosa-Neto +17 more
TL;DR: Evidence is provided of frontal cortical involvement of tau pathology in behavioral/dysexecutive AD and the need for consensus clinical criteria in this syndrome is highlighted.
Journal ArticleDOI
Vascular retinal biomarkers improves the detection of the likely cerebral amyloid status from hyperspectral retinal images.
Sayed Mehran Sharafi,Jean-Philippe Sylvestre,Claudia Chevrefils,Jean-Paul Soucy,Sylvain Beaulieu,Tharick A. Pascoal,Jean Daniel Arbour,Marc-André Rhéaume,Alain Robillard,Céline Chayer,Pedro Rosa-Neto,Sulantha Mathotaarachchi,Ziad S. Nasreddine,Serge Gauthier,Frédéric Lesage +14 more
TL;DR: The relationship between retinal image features and β‐amyloid burden in the brain is investigated with the aim of developing a noninvasive method to predict the deposition of Aβ in thebrain of patients with Alzheimer's disease.
Journal ArticleDOI
Effects of rivastigmine on common symptomatology of Alzheimer’s disease (EXPLORE)
Serge Gauthier,Angela Juby,William B. Dalziel,Bonita Rehel,Robyn Schecter,Explore investigators +5 more
TL;DR: It is demonstrated that a considerable proportion of rivastigmine-treated patients experience improvements on each of the six symptoms studied, adding further support to previous randomised, clinical studies showing benefit of rivetigmine in AD.