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Serge Gauthier

Researcher at McGill University

Publications -  715
Citations -  61038

Serge Gauthier is an academic researcher from McGill University. The author has contributed to research in topics: Dementia & Disease. The author has an hindex of 93, co-authored 637 publications receiving 52775 citations. Previous affiliations of Serge Gauthier include Hamamatsu University School of Medicine & La Salle University.

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Benefits of combined cholinesterase inhibitor and memantine treatment in moderate–severe Alzheimer's disease

TL;DR: The evidence for the short‐ and long‐term efficacy of combination therapy in AD is reviewed, with a focus on the use of statins and chemotherapy in combination.
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The assessment of recognition memory using the Remember/Know procedure in amnestic mild cognitive impairment and probable Alzheimer's disease.

TL;DR: The R/K procedure can characterize different aspects of recognition memory performance in persons with aMCI or AD, and reveals that AD patients were more liberal than a MCI and control participants when providing Know responses.
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Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging.

TL;DR: The biological basis of neuroinflammatory changes in AD is addressed, therapeutic strategies using anti-inflammatory compounds are underscored, and light is shed on the possibility of tracking neuroinflammation in vivo using PET imaging ligands.
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Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease.

TL;DR: In this article, a voxel-based interaction model was built to test the associations between continuous measurements of CSF biomarkers, [18F]florbetapapir and standardized uptake value ratios (SUVR), rather than the sum of their independent effects, was associated with a 24-month metabolic decline.