S
Serge Gauthier
Researcher at McGill University
Publications - 715
Citations - 61038
Serge Gauthier is an academic researcher from McGill University. The author has contributed to research in topics: Dementia & Disease. The author has an hindex of 93, co-authored 637 publications receiving 52775 citations. Previous affiliations of Serge Gauthier include Hamamatsu University School of Medicine & La Salle University.
Papers
More filters
Journal ArticleDOI
Benefits of combined cholinesterase inhibitor and memantine treatment in moderate–severe Alzheimer's disease
TL;DR: The evidence for the short‐ and long‐term efficacy of combination therapy in AD is reviewed, with a focus on the use of statins and chemotherapy in combination.
Journal ArticleDOI
Clinical effects of choline in Alzheimer's disease.
Journal ArticleDOI
The assessment of recognition memory using the Remember/Know procedure in amnestic mild cognitive impairment and probable Alzheimer's disease.
TL;DR: The R/K procedure can characterize different aspects of recognition memory performance in persons with aMCI or AD, and reveals that AD patients were more liberal than a MCI and control participants when providing Know responses.
Journal ArticleDOI
Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging.
Eduardo R. Zimmer,Eduardo R. Zimmer,Antoine Leuzy,Andrea Lessa Benedet,Andrea Lessa Benedet,John C.S. Breitner,Serge Gauthier,Pedro Rosa-Neto +7 more
TL;DR: The biological basis of neuroinflammatory changes in AD is addressed, therapeutic strategies using anti-inflammatory compounds are underscored, and light is shed on the possibility of tracking neuroinflammation in vivo using PET imaging ligands.
Journal ArticleDOI
Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease.
Tharick A. Pascoal,Sulantha Mathotaarachchi,Sara Mohades,Andrea Lessa Benedet,Andrea Lessa Benedet,Chang-Oh Chung,Monica Shin,Seqian Wang,Tom Beaudry,Min Su Kang,Jean-Paul Soucy,Aurélie Labbe,Serge Gauthier,Pedro Rosa-Neto +13 more
TL;DR: In this article, a voxel-based interaction model was built to test the associations between continuous measurements of CSF biomarkers, [18F]florbetapapir and standardized uptake value ratios (SUVR), rather than the sum of their independent effects, was associated with a 24-month metabolic decline.