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Serge Gauthier
Researcher at McGill University
Publications - 715
Citations - 61038
Serge Gauthier is an academic researcher from McGill University. The author has contributed to research in topics: Dementia & Disease. The author has an hindex of 93, co-authored 637 publications receiving 52775 citations. Previous affiliations of Serge Gauthier include Hamamatsu University School of Medicine & La Salle University.
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Journal ArticleDOI
The effects of donepezil in Alzheimer's disease - results from a multinational trial.
Alistair Burns,Martin N. Rossor,Jane Hecker,Serge Gauthier,H. Petit,Hans-Jürgen Möller,S. L. Rogers,L. T. Friedhoff +7 more
TL;DR: The results of this study confirm that donepezil is effective and well tolerated in treating the symptoms of mild to moderately severe AD.
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Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
Hao Li,Sally Wetten,Li Li,Pamela L. St. Jean,Ruchi Upmanyu,Linda Surh,David A. Hosford,Michael R. Barnes,James David Briley,Michael Borrie,Natalie Coletta,Richard Delisle,Daniella Dhalla,Margaret G. Ehm,Howard Feldman,Luis Fornazzari,Serge Gauthier,Neil Goodgame,Danilo Guzman,Sandra Hammond,Paul Hollingworth,Ging-Yuek Robin Hsiung,Joan Johnson,Devon D. Kelly,Ron Keren,Andrew Kertesz,Karen S. King,Simon Lovestone,Inge Loy-English,Paul M. Matthews,Michael John Owen,Mary Plumpton,William Pryse-Phillips,Rab K. Prinjha,Jill C. Richardson,Ann M. Saunders,Andrew J. Slater,Peter St George-Hyslop,Sandra W. Stinnett,Jina E. Swartz,Rachel L. Taylor,John Wherrett,Julie Williams,David P. Yarnall,Rachel A. Gibson,Michael C. Irizarry,Lefkos T. Middleton,Allen D. Roses +47 more
TL;DR: The genomewide association analysis again identified the APOE linkage disequilibrium region as the strongest genetic risk factor for AD.
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Proposed diagnostic criteria for apathy in Alzheimer's disease and other neuropsychiatric disorders.
Philippe Robert,Chiadi U. Onyike,Albert F.G. Leentjens,Kathy Dujardin,Pauline Aalten,Sergio E. Starkstein,Frans R.J. Verhey,J. Yessavage,J.-P. Clément,Dominique Drapier,Franck Baylé,Michel Benoit,Patrice Boyer,P. M. Lorca,Florence Thibaut,Serge Gauthier,George T. Grossberg,Bruno Vellas,J. Byrne +18 more
TL;DR: The focus of the task force work reported here is to develop criteria for apathy that will be widely accepted, have clear operational steps, and be easily applied in practice and research settings.
Journal ArticleDOI
Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats.
TL;DR: Histological analysis of a subset of aged animals showed that, while both AU and AI animals showed neuron loss in the pyramidal cell fields of the hippocampus, the loss was significantly greater in the AI animals, which showed clear evidence of increased HPA activity.
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The psychological and physical health of family members caring for an elderly person with dementia.
Mona Baumgarten,Renaldo N. Battista,Claire Infante-Rivard,James A. Hanley,Rubin Becker,Serge Gauthier +5 more
TL;DR: The results suggest that family caregivers of elderly persons with dementia might benefit from careful monitoring of their health status, and from greater access to specialized support services.