S
Shinji Kasai
Researcher at National Institutes of Health
Publications - 109
Citations - 3807
Shinji Kasai is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & Knockdown resistance. The author has an hindex of 33, co-authored 92 publications receiving 3209 citations. Previous affiliations of Shinji Kasai include University of Tsukuba & Cornell University.
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Journal ArticleDOI
Pyrethroid resistance in Aedes aegypti and Aedes albopictus: Important mosquito vectors of human diseases
TL;DR: The status of pyrethroid resistance in A. aegypti and A. albopictus is reviewed, mechanisms of resistance, fitness costs associated with resistance alleles and suggestions for future research are presented.
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Genome of the house fly, Musca domestica L., a global vector of diseases with adaptations to a septic environment
Jeffrey G. Scott,Wesley C. Warren,Leo W. Beukeboom,Daniel Bopp,Andrew G. Clark,Sarah D. Giers,Monika Hediger,Andrew K. Jones,Shinji Kasai,Cheryl A. Leichter,Ming Li,Richard P. Meisel,Patrick Minx,Terence D Murphy,David R. Nelson,William R. Reid,Frank D. Rinkevich,Hugh M. Robertson,Timothy B. Sackton,David B. Sattelle,Francoise Thibaud-Nissen,Chad Tomlinson,Louis van de Zande,Kimberly K. O. Walden,Richard K. Wilson,Nannan Liu +25 more
TL;DR: The house fly genome provides a rich resource for enabling work on innovative methods of insect control, for understanding the mechanisms of insecticide resistance, genetic adaptation to high pathogen loads, and for exploring the basic biology of this important pest.
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Mechanisms of Pyrethroid Resistance in the Dengue Mosquito Vector, Aedes aegypti: Target Site Insensitivity, Penetration, and Metabolism
Shinji Kasai,Osamu Komagata,Kentaro Itokawa,Toshio Shono,Lee Ching Ng,Mutsuo Kobayashi,Takashi Tomita +6 more
TL;DR: In vivo metabolism studies showed that the SP strain excreted permethrin metabolites more rapidly than a susceptible SMK strain, and in vitro metabolism studies indicated an association of P450s with resistance, suggesting that cytochrome P450 monooxygenases (P450s) play an important role in resistance development.
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An amino acid substitution attributable to insecticide-insensitivity of acetylcholinesterase in a Japanese encephalitis vector mosquito, Culex tritaeniorhynchus.
Takeshi Nabeshima,Akio Mori,Toshinori Kozaki,Yoichi Iwata,Osamu Hidoh,Shizuko Harada,Shinji Kasai,David W. Severson,Yoshiaki Kono,Takashi Tomita +9 more
TL;DR: The F455W replacement in the Ace2 gene is solely responsible for the insecticide-insensitivity of AChE in TYM mosquitoes.
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Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challenges.
Isabelle Dusfour,John Vontas,John Vontas,Jean-Philippe David,David Weetman,Dina M. Fonseca,Vincent Corbel,Kamaraju Raghavendra,Mamadou B. Coulibaly,Ademir Jesus Martins,Shinji Kasai,Fabrice Chandre +11 more
TL;DR: A framework for the implementation of IRM strategies for Aedes mosquito vectors is proposed based on the lessons taken from resistance strategies used for other vector species and agricultural pests, and the value of existing tools for resistance monitoring is evaluated.