S
Shyamal Wahie
Researcher at County Durham and Darlington NHS Foundation Trust
Publications - 9
Citations - 448
Shyamal Wahie is an academic researcher from County Durham and Darlington NHS Foundation Trust. The author has contributed to research in topics: Frontal fibrosing alopecia & Ultraviolet therapy. The author has an hindex of 5, co-authored 9 publications receiving 284 citations. Previous affiliations of Shyamal Wahie include Leicester Royal Infirmary & Durham University.
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Journal ArticleDOI
Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic, non-inferiority, randomised controlled trial
Hywel C Williams,Fenella Wojnarowska,Gudula Kirtschig,Gudula Kirtschig,James Mason,Thomas R. Godec,Enno Schmidt,Joanne R Chalmers,Margaret Childs,S. Walton,Karen E. Harman,A. Chapman,Diane Whitham,Andrew J. Nunn,J Adams,V Akhras,Alexander Vincent Anstey,C Barnard,H K Bell,S Blackford,Eva-B. Bröcker,A Carmichael,R.R. Coelho,Fiona Craig,K Davies,Robert Ellis,John C. English,Regine Gläser,Richard Groves,C Günthert,P J Hampton,N. Hepburn,Rainer Hügel,K. Hussain,John R. Ingram,Alison M Layton,Nick J. Levell,V Lewis,H Malhomme,A Omerod,Girish Khandubhai Patel,R Rallan,Jane Ravenscroft,H Santander,Kerstin Steinbrink,Michael Sticherling,C Thomas,M Vatve,N. van Beek,V Venning,Emma Veysey,R. Wachsmuth,Shyamal Wahie,B Walker,M Walsh,J Wee,M Westmoreland,G Wong,Adam Ferguson,Indre Verpetinske,Emilia Duarte-Williamson,Fiona Antony,Chris Bower,David Gawkrodger,Kathy Taghipour,M G S Dunnill,Alex Waters,Walter Bottomley,Andrew M Wright,Jane C. Sterling,Adzura Azam,Sam Gibbs,Thomas A. Luger,Ingrid Salvary,Chris Lovell,Andrew Ilchyshyn,Karen Gibbon,Marinella Nik,Robert Charles-Holmes,A Lloyd Lavery +79 more
TL;DR: Starting patients on doxycycline is non-inferior to standard treatment with oral prednisolone for short-term blister control in bullous pemphigoid and significantly safer in the long-term.
Journal ArticleDOI
HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis
Nick Dand,Michael Duckworth,David Baudry,Alice Russell,Charles Curtis,Charles Curtis,Sang Hyuck Lee,Sang Hyuck Lee,Ian Evans,K.J. Mason,Ali Alsharqi,Gabrielle Becher,A. David Burden,Richard Geoffrey Goodwin,K.E. McKenna,Ruth Murphy,Ruth Murphy,Gayathri K. Perera,Radu Rotarescu,Shyamal Wahie,Andrew Wright,Andrew Wright,Nick J. Reynolds,Nick J. Reynolds,Richard B. Warren,Christopher E.M. Griffiths,Catherine H. Smith,Michael A. Simpson,Jonathan Barker,Marilyn Benham,Sagair Hussain,Brian Kirby,Linda Lawson,Kathleen McElhone,Anthony Ormerod,C. M. Owen,Michael R. Barnes,Paola Di Meglio,Richard Emsley,Andrea Evans,Katherine Payne,Deborah D. Stocken +41 more
TL;DR: This large observational study suggests that reference to HLA-C*06:02 status could offer substantial clinical benefit when selecting treatments for severe psoriasis.
Journal ArticleDOI
Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02
Christos Tziotzios,Christos Petridis,Nick Dand,Chrysanthi Ainali,Jake Saklatvala,Venu Pullabhatla,Alexandros Onoufriadis,Rashida Pramanik,David Baudry,Sang Hyuck Lee,Kristie Wood,Lu Liu,Seth D. Seegobin,Gregory A Michelotti,Su M. Lwin,Evangelos A A Christou,Charles Curtis,Emanuele de Rinaldis,Alka Saxena,Susan Holmes,Matthew Harries,Ioulios Palamaras,Fiona Cunningham,Gregory Parkins,M R Kaur,Paul Farrant,Andrew J. G. McDonagh,Andrew G. Messenger,Jennifer Jones,Jennifer Jones,V. Jolliffe,Iaisha Ali,Michael R. Ardern-Jones,Charles E. Mitchell,Nigel Burrows,Ravinder Atkar,Cedric Charles Banfield,Anton B. Alexandroff,Caroline Champagne,Hywel L Cooper,Sergio Vano-Galvan,Ana María Molina-Ruiz,Nerea Ormaechea Perez,Girish K Patel,A. E. Macbeth,Melanie Page,A. S. Bryden,Megan Mowbray,Shyamal Wahie,Keith Armstrong,Nicola Cooke,Mark Goodfield,Irene Man,David de Berker,Giles Dunnill,A. Takwale,Archana Rao,Tee-Wei Siah,Rodney Sinclair,Martin S Wade,Ncoza C. Dlova,Jane Setterfield,Fiona Lewis,Kapil Bhargava,Niall Kirkpatrick,Xavier Estivill,Catherine M. Stefanato,Carsten Flohr,Tim D. Spector,Fiona M. Watt,Catherine H. Smith,Jonathan Barker,David A. Fenton,Michael A. Simpson,John A. McGrath +74 more
TL;DR: Four genetic loci associated with FFA are identified by GWAS followed by Bayesian fine-mapping, co-localisation and HLA imputation which highlights HLA-B*07:02 as a risk factor.
Journal ArticleDOI
Clinical outcomes and response of patients applying topical therapy for pyoderma gangrenosum: a prospective cohort study
Kim S Thomas,Anthony Ormerod,Fiona E. Craig,Nicola Greenlaw,John Norrie,Eleanor J Mitchell,James Mason,Graham A. Johnston,Shyamal Wahie,Hywel Williams +9 more
TL;DR: Topical therapy is potentially an effective first-line treatment for PG that avoids the possible side effects associated with systemic therapy and remains unclear whether more severe disease will respond adequately to topical therapy alone.
Journal ArticleDOI
Randomized controlled trial of topical corticosteroid and home-based narrowband ultraviolet B for active and limited vitiligo: results of the HI-Light Vitiligo Trial.
Kim S Thomas,Jonathan M. Batchelor,Perways Akram,Joanne R Chalmers,Rachel H. Haines,Garry Meakin,Lelia Duley,Jane Ravenscroft,Anne Rogers,Tracey Sach,Miriam Santer,Wei Tan,Jennifer White,Maxine E Whitton,Hywel C Williams,S T Cheung,H Hamad,Andrew Wright,John R. Ingram,Nick J. Levell,J. M. R. Goulding,A Makrygeorgou,Anthony Bewley,M. Ogboli,J Stainforth,Adam Ferguson,B. Laguda,Shyamal Wahie,R Ellis,J Azad,A Rajasekaran,Viktoria Eleftheriadou,Alan A Montgomery +32 more
TL;DR: It is necessary to select patients suitable for vitiligo treatment on the basis of prior history and once they have provided informed consent for the treatment.