S
Si-Xue Cheng
Researcher at Wuhan University
Publications - 238
Citations - 12634
Si-Xue Cheng is an academic researcher from Wuhan University. The author has contributed to research in topics: Drug carrier & Micelle. The author has an hindex of 54, co-authored 236 publications receiving 10754 citations. Previous affiliations of Si-Xue Cheng include Sichuan University & University of South China.
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Thermo-sensitive polymeric micelles based on poly(N-isopropylacrylamide) as drug carriers
TL;DR: In this article, the authors present a review of the recent developments in this field, and focus on two categories of PNIPAAm-based copolymer micelles as smart drug delivery systems.
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Multifunctional envelope-type mesoporous silica nanoparticles for tumor-triggered targeting drug delivery.
Jing Zhang,Zhefan Yuan,Ya Wang,Wei-Hai Chen,Guo-Feng Luo,Si-Xue Cheng,Ren-Xi Zhuo,Xian-Zheng Zhang +7 more
TL;DR: A novel type of cellular-uptake-shielding multifunctional envelope-type mesoporous silica nanoparticle designed for tumor-triggered targeting drug delivery to cancerous cells was designed and in vitro study demonstrated that MEMSN was shielded against normal cells.
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Drug self-delivery systems for cancer therapy
TL;DR: This review presents a comprehensive summary of the recent advances in carrier-assistant drug delivery systems for cancer therapy and emphatically discusses some representative achievements of these DSDSs for passive or/and positive targeting therapy, combinational therapy as well as theranostics.
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Switching Apoptosis to Ferroptosis: Metal–Organic Network for High-Efficiency Anticancer Therapy
Di-Wei Zheng,Di-Wei Zheng,Qi Lei,Jing-Yi Zhu,Jin-Xuan Fan,Chu-Xin Li,Cao Li,Zushun Xu,Si-Xue Cheng,Xian-Zheng Zhang +9 more
TL;DR: MON encapsulated with p53 plasmid (MON-p53) was designed to eradicate cancer cells via ferroptosis/apoptosis hybrid pathway by harnessing the recently discovered oxidative stress regulation ability of p53 and the Fenton reaction inducing capability of metal-organic network.
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Functionalized amphiphilic hyperbranched polymers for targeted drug delivery.
TL;DR: The results showed the drug-loaded nanoparticles exhibited enhanced cell inhibition because folate targeting increased the cytotoxicity of drug- loaded nanoparticles against folate receptor expressing tumor cells.