S
Steffen Stenger
Researcher at University of Ulm
Publications - 134
Citations - 14900
Steffen Stenger is an academic researcher from University of Ulm. The author has contributed to research in topics: Mycobacterium tuberculosis & Immune system. The author has an hindex of 46, co-authored 119 publications receiving 13155 citations. Previous affiliations of Steffen Stenger include University of Erlangen-Nuremberg & University of California.
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Journal ArticleDOI
Cytokine interactions in experimental cutaneous leishmaniasis. Interleukin 4 synergizes with interferon‐γ to activate murine macrophages for killing of Leishmania major amastigotes
TL;DR: Evidence is presented that the synergistic action of IL 4 and IFN‐γ occurs via an L‐arginine‐dependent killing pathway, and it is concluded that IL 4 provides a strong stimulus for the killing of intracellular L. major AM provided low concentrations of IFN-γ are present.
Posted ContentDOI
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition
Caterina Prelli Bozzo,Rayhane Nchioua,Meta Volcic,Jana Krüger,Sandra Heller,Christina M Stuerzel,Dorota Kmiec,Dorota Kmiec,Carina Conzelmann,Janis A. Müller,Fabian Zech,Desiree Schütz,Lennart Koepke,Elisabeth Braun,Rüdiger Groß,Lukas Wettstein,Tatjana Weil,Johanna Weiss,Daniel Sauter,Jan Münch,Federica Diofano,Christine Goffinet,Alberto Catanese,Michael Schön,Tobias M. Boeckers,Steffen Stenger,Kei Sato,Steffen Just,Alexander Kleger,Konstantin M. J. Sparrer,Frank Kirchhoff +30 more
TL;DR: The results show that IFITM proteins are important cofactors for SARS-CoV-2 infection of human cell types representing in vivo targets for viral transmission, dissemination and pathogenesis and suitable targets for therapeutic approaches.
Journal ArticleDOI
L-N6-(1-iminoethyl)-lysine potently inhibits inducible nitric oxide synthase and is superior to NG-monomethyl-arginine in vitro and in vivo.
TL;DR: It is concluded that L-N6-(1-iminoethyl)-lysine should be used instead of NG-monomethyl-L-arginine for potent suppression of inducible NO-synthase in vitro and in vivo.
Journal ArticleDOI
NK Cells, but Not NKT Cells, Are Involved in Pseudomonas aeruginosa Exotoxin A-Induced Hepatotoxicity in Mice
Katrin A. Mühlen,Jens Schümann,Frederick Wittke,Steffen Stenger,Nico van Rooijen,Luc Van Kaer,Gisa Tiegs +6 more
TL;DR: It is demonstrated that NK cells, activated and recruited independently of NKT cells, contribute to PEA-induced T cell-dependent liver injury in mice.
Journal ArticleDOI
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection.
Lukas Wettstein,Tatjana Weil,Carina Conzelmann,Janis A. Müller,Rüdiger Groß,Maximilian Hirschenberger,Alina Seidel,Susanne Klute,Fabian Zech,Caterina Prelli Bozzo,Nico Preising,Giorgio Fois,Robin Lochbaum,Philip Maximilian Knaff,Volker Mailänder,Ludger Ständker,Dietmar Rudolf Thal,Dietmar Rudolf Thal,Christian Schumann,Steffen Stenger,Alexander Kleger,Günter Lochnit,Benjamin Mayer,Yasser B. Ruiz-Blanco,Markus Hoffmann,Markus Hoffmann,Konstantin M. J. Sparrer,Stefan Pöhlmann,Elsa Sanchez-Garcia,Frank Kirchhoff,Manfred Frick,Jan Münch +31 more
TL;DR: In this article, a peptide/protein library derived from bronchoalveolar lavage for inhibitors of SARS-CoV-2 spike-driven entry was generated and screened.