S
Steffen Stenger
Researcher at University of Ulm
Publications - 134
Citations - 14900
Steffen Stenger is an academic researcher from University of Ulm. The author has contributed to research in topics: Mycobacterium tuberculosis & Immune system. The author has an hindex of 46, co-authored 119 publications receiving 13155 citations. Previous affiliations of Steffen Stenger include University of Erlangen-Nuremberg & University of California.
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Journal ArticleDOI
New insights into the interaction of Mycobacterium tuberculosis and human macrophages
Heiko Bruns,Steffen Stenger +1 more
TL;DR: There is emerging evidence demonstrating that human macrophages are equipped with additional antimicrobial effector functions that have been identified as mechanisms to restrict mycobacterial proliferation.
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Carrageenan containing over-the-counter nasal and oral sprays inhibit SARS-CoV-2 infection of airway epithelial cultures.
Desiree Schütz,Carina Conzelmann,Giorgio Fois,Rüdiger Groß,Tatjana Weil,Lukas Wettstein,Steffen Stenger,Alexander N. Zelikin,Thomas K. Hoffmann,Manfred Frick,Janis A. Müller,Jan Münch +11 more
TL;DR: In this article, the antiviral effect of selected nasal and oral sprays on virus infection in vitro was analyzed and two nose sprays showed virucidal activity but were cytotoxic precluding further analysis in cell culture.
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2,4-Diamino-6-hydroxypyrimidine, an inhibitor of tetrahydrobiopterin synthesis, downregulates the expression of iNOS protein and mRNA in primary murine macrophages
Christian Bogdan,Ernst R. Werner,Steffen Stenger,Helmut Wachter,Martin Rbllinghoff,Gabriele Werner-Felmayer +5 more
TL;DR: It is demonstrated that in interferon‐γ‐activated murine peritoneal macrophages DAHP suppresses the expression of iNOS mRNA and protein in a BH4‐independent manner and, thus, acts by a novel mechanism.
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Increased frequencies of pulmonary regulatory T-cells in latent Mycobacterium tuberculosis infection
Christian Herzmann,Martin Ernst,Stefan Ehlers,Steffen Stenger,Jeroen Maertzdorf,Giovanni Sotgiu,Christoph Lange +6 more
TL;DR: Investigation of specific immune responses following exposure to Mycobacterium tuberculosis in humans and the role of regulatory T (Treg) cells in the immune control of latent infection with M. tuberculosis in healthcare workers regularly exposed to tuberculosis (TB) patients and in household TB contacts in Germany indicates a limited local immune response.
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SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3.
Utkarsh Tripathi,Rayhane Nchioua,Larissa G.P. Langhi Prata,Yi Zhu,Erin O. Wissler Gerdes,Nino Giorgadze,Tamar Pirtskhalava,Erik S. Parker,Ailing Xue,Jair Machado Espindola-Netto,Steffen Stenger,Paul D. Robbins,Laura J. Niedernhofer,Stephanie L. Dickinson,David B. Allison,Frank Kirchhoff,Konstantin Maria Johannes Sparrer,Tamar Tchkonia,James L. Kirkland +18 more
TL;DR: In this paper, the authors show that SARS-CoV-2 induces senescence in human non-senescent cells and exacerbates the SASP in human senescent cells through TLR-3.