Sverre E. Kjeldsen

TL;DR: The benefit of losartan vs atenolol is consistent with the overall conclusion of the LIFE study, although the treatment effect appeared largest in non-smokers, and a borderline significant trend suggested decreasing benefit ofLosartan Vs atanolol for stroke prevention from never- to previous to current smoking status.

TL;DR: The overall BP lowering effect of RDN seems rather limited and the characteristics of the true responders remain largely unknown, Accordingly, RDN is not ready for clinical practice.

TL;DR: Investigation of the intracellular concentrations of magnesium, potassium and sodium in 50-year-old, otherwise healthy white men with never treated, essential hypertension and in normotensive control subjects found increased intrACEllular magnesium probably unrelated to intrace cellular potassium-sodium imbalance in never treated and essential hypertension.

TL;DR: The higher risks of myocardial infarction and stroke in patients randomized to valsartan versus amlodipine were related to the drugs’ different blood pressure modulating profiles, and the risk of congestive heart failure with vALSartan was lower, independent of the less favorable blood Pressure modulating profile.

TL;DR: For instance, this article found that preeclamptic women had increased venous plasma-free adrenaline (45 +/- 5 vs 27 +/- 2 pg/ml, mean +/- SE, P less than 0.01) compared with fifteen normotensive pregnant women, supporting increased sympathetic nervous tone in the development of preeclampsia.