S
Sverre E. Kjeldsen
Researcher at University of Oslo
Publications - 771
Citations - 95426
Sverre E. Kjeldsen is an academic researcher from University of Oslo. The author has contributed to research in topics: Blood pressure & Left ventricular hypertrophy. The author has an hindex of 94, co-authored 735 publications receiving 89059 citations. Previous affiliations of Sverre E. Kjeldsen include University of Michigan & Cornell University.
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Better drug adherence improves blood pressure control and lowers cardiovascular disease outcomes - from single pill combinations to monitoring of a nationwide health insurance database.
TL;DR: In this paper, pharmacological treatment of hypertension may be successful with control of the high blood pressure (BP) and prevention of cardiovascular (CV) disease outcomes if patients take their medication as...
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Response to letters from Torp-Pedersen and colleagues and de Courson and colleagues.
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S-52-1: cardiovascular outcomes in hypertensive patients who discontinue study medication in a large outcome trial. the life study.
Kristian Wachtell,Stevo Julius,Peter M. Okin,Anders M. Greve,Richard B. Devereux,Suzanne Oparil,Sverre E. Kjeldsen,Kurt Boman +7 more
TL;DR: In this paper , Cox proportional hazards models were used to identify baseline variables that had a significant impact on the occurrence of the primary composite endpoint (cardiovascular death, stroke, and myocardial infarction) in 9,193 hypertensive patients and left ventricular hypertrophy (LVH) in the LIFE study.
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Abstract P221: Cardiovascular Outcomes In Hypertensive Patients Who Discontinue Study Medication In A Large Outcome Trial. The Life Study.
Kristian Wachtell,Stevo Julius,Peter M. Okin,Anders M. Greve,Richard B. Devereux,Suzanne Oparil,Sverre E. Kjeldsen,Kurt Boman +7 more
TL;DR: Patients who discontinued the study drug had, on average, more previous and concurrent cardiovascular disease than those who continued until the study ended, and too high risk in an outcome study implies early drug discontinuation and thus reduction in the study power.
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Response to Letter by Morris et al Regarding Article, “Low Heart Rates Predict Incident Atrial Fibrillation in Healthy Middle-Aged Men” by Grundvold et al
Irene Grundvold,Per Torger Skretteberg,Kristian Engeseth,Knut Gjesdal,Sverre E. Kjeldsen,Harald Arnesen,Johan Bodegard,Knut Liestøl,Gunnar Erikssen,Jan Erikssen +9 more
TL;DR: It is speculated that vagal dominance might be involved, causing relative bradycardia and larger stroke volumes both at rest and during moderate exercise, as well as more atrial stretch resulting in remodeling, which may be electric.