Sverre E. Kjeldsen

TL;DR: In conclusion, losartan did not influence the circulating levels of ET-1 in basal condition or during acute hyperinsulinemia, whereas a significant decrease in plasmaET-1 occurred during acuteHyperinsulinesia, and a significant inverse correlation demonstrated between basal levels of plasma ET- 1 and the insulin-stimulated glucose uptake could point to a possible regulatory influence of ET -1 production on glucose metabolism or vice versa.

TL;DR: The very recent American College of Physicians/American Academy of Family Practitioners guidelines were put together by a set of authors and consultants without any expertise in the topic under discussion, that is, hypertension.

TL;DR: Although hypertensive patients with low baseline HDL cholesterol levels have a higher incidence of diabetes mellitus, whether changing levels of HDL over time are more strongly related to the risk of new diabetes in hypertensive Patients has not been examined.

TL;DR: In this high-risk population of patients with isolated systolic hypertension and left ventricular hypertrophy, lower hemoglobin at baseline was associated with higher probability of cardiovascular death, and decrease in hemoglobin over time was associatedwith higher probability with cardiovascular death or stroke.

TL;DR: Prescribing candesartan for the primary treatment of hypertension results in lower long-term health-care costs compared with losartan, and the mean total costs per patient were 10 369 Swedish kronor (95% confidence interval: 3109–17 629) higher in theLosartan group.