Thomas F. Lüscher

TL;DR: The effects of ET-1 but not of U-46619 are enhanced in reperfused hearts, which may contribute to the delayed recovery of the postischemic reperfusion myocardium.

TL;DR: The results show that captopril is a potent blood pressure lowering agent in severe and therapy resistant hypertension and the vast majority of patients required concomitant therapy with a diuretic and/or a betablocker.

TL;DR: In patients with hyperhomocysteinemia and a high risk for cardiovascular events (i.e. patients with multiple risk factors or established atherosclerotic vascular disease), the dietary intake of folic acid and vitamins B6 and B12 should be optimized.

TL;DR: Arterial injury does not correlate with the amount of neointimal hyperplasia following DES implantation, and conventionally aggressive DES implantations techniques do not adversely affect long-term outcome with respect to restenosis.

TL;DR: In this paper, the authors demonstrate that lifelong dietary ALA decreases platelet hyperresponsiveness and thrombus formation in aged mice, which can be attributed to alteration of microbial composition and reduction of its metabolite trimethylamine N-oxide and inflammatory mediators including TNF-α, as well as upregulated production of short-chain fatty acid acetate.