T
Thomas F. Lüscher
Researcher at University of Zurich
Publications - 1613
Citations - 88517
Thomas F. Lüscher is an academic researcher from University of Zurich. The author has contributed to research in topics: Endothelium & Myocardial infarction. The author has an hindex of 134, co-authored 1560 publications receiving 79034 citations. Previous affiliations of Thomas F. Lüscher include University of Texas Southwestern Medical Center & Durham University.
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Will endothelin receptor antagonists have a role in heart failure
TL;DR: MixedET(A/B) and selective ET(A) receptor antagonists showed promising hemodynamic and symptomatic improvements in patients with heart failure and on the clinical outcome of patients with CHF.
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The year in cardiology 2016: acute coronary syndromes
TL;DR: The year 2016 brought us several studies on the pathophysiology of acute coronary syndrome (ACS), in particular, on the role of basophils and eosinophils in the mechanism of disease, and important new data on the duration of dual antiplatelet therapy (DAPT) and on the management of the growing population of very elderly.
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CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research
Dipak Kotecha,Folkert W. Asselbergs,Stephan Achenbach,Stefan D. Anker,Dan Atar,Colin Baigent,Amitava Banerjee,Birgit Beger,Gunnar Brobert,Barbara Casadei,Cinzia Ceccarelli,Martin R. Cowie,Filippo Crea,Maureen Cronin,Spiros Denaxas,Andrea Derix,Donna Fitzsimons,Martin Fredriksson,Chris P Gale,Georgios V. Gkoutos,Wim G. Goettsch,Harry Hemingway,Martin Ingvar,Adria Jonas,Robert T. Kazmierski,Susanne Logstrup,R. Thomas Lumbers,Thomas F. Lüscher,Paul McGreavy,Ileana L. Piña,Lothar Roessig,Carl Steinbeisser,Mats Sundgren,Benoit Tyl,Ghislaine J. M. W. van Thiel,Kees van Bochove,Panos E. Vardas,Tiago Villanueva,Marilena Vrana,Wim E.J. Weber,Franz Weidinger,Stephan Windecker,Angela M. Wood,Diederick E. Grobbee +43 more
TL;DR: The CODE-EHR Minimum Standards Framework as discussed by the authors was proposed as a means to improve the design of studies, enhance transparency and develop a roadmap towards more robust and effective utilisation of healthcare data for research purposes.
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Atherosclerosis and CAD.
TL;DR: The authors conclude that in STEMI patients who underwent primary PCI, high-intensity statin therapy with rosuvastatin for 13 months with a primary IVUS endpoint was the change in percentage atheroma volume, and the necrotic core was unaffected, as was the number of thin cap fibroatheromas.
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Development of nitrate tolerance in human arteries and veins: comparison of nitroglycerin and SPM 5185.
U. Arnet,Zhihong Yang,R. Siebenmann,L. K. Von Segesser,M. I. Turina,Peter Stulz,Thomas F. Lüscher +6 more
TL;DR: Compared to nitroglycerin, the new cysteine-containing mononitrate SPM 5185 exhibited a lower sensitivity but comparable maximal relaxation in arteries and veins, and seems to be less prone to the development of tolerance, which may be advantageous during chronic nitrate therapy.