T
Thomas F. Lüscher
Researcher at University of Zurich
Publications - 1613
Citations - 88517
Thomas F. Lüscher is an academic researcher from University of Zurich. The author has contributed to research in topics: Endothelium & Myocardial infarction. The author has an hindex of 134, co-authored 1560 publications receiving 79034 citations. Previous affiliations of Thomas F. Lüscher include University of Texas Southwestern Medical Center & Durham University.
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Journal ArticleDOI
Endothelial Nitric Oxide Synthase Host Defense Enzyme of the Endothelium
TL;DR: The physiology of superoxide generation by endothelial nitric oxide synthase (eNOS) is explored, the so-called "uncoupled" state of the enzyme, and it is proposed that this uncoupled state may contribute to defense against infections.
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Real-Time Left Ventricular Pressure-Volume Loops During Percutaneous Mitral Valve Repair With the MitraClip System
Oliver Gaemperli,Patric Biaggi,Remo Gugelmann,Martin Osranek,Jan J. Schreuder,Ines Bühler,Daniel Sürder,Thomas F. Lüscher,Christian Felix,Dominique Bettex,Jürg Grünenfelder,Roberto Corti +11 more
TL;DR: Percutaneous mitral valve repair improves hemodynamic profiles and induces reverseleft ventricular remodeling by reducing left ventricular preload while preserving contractility and in nonsurgical candidates with compromised left Ventricular function, MitraClip therapy could be considered an alternative to surgical mitral valves repair.
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Takotsubo cardiomyopathy has a unique cardiac biomarker profile: NT-proBNP/myoglobin and NT-proBNP/troponin T ratios for the differential diagnosis of acute coronary syndromes and stress induced cardiomyopathy
Georg M. Fröhlich,Boris Schoch,Florian A. Schmid,Philipp Keller,Isabella Sudano,Thomas F. Lüscher,Georg Noll,Frank Ruschitzka,Frank Enseleit +8 more
TL;DR: Takotsubo cardiomyopathy goes along with a singular cardiac biomarker profile, which might be useful to identify patients with TC among patients presenting with acute coronary syndromes (ACS).
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Endothelium-Dependent Relaxations in Human Arteries
TL;DR: In contracted arterial rings, acetylcholine caused endothelium-dependent relaxations that were not inhibited by indomethacin in either artery but were significantly augmented in the renal artery, indicating that the relaxations are mediated by the release of an endotHelium-derived relaxing factor (or factors) rather than the releaseof prostacyclin.
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Differential blood pressure effects of ibuprofen, naproxen, and celecoxib in patients with arthritis: the PRECISION-ABPM (Prospective Randomized Evaluation of Celecoxib Integrated Safety Versus Ibuprofen or Naproxen Ambulatory Blood Pressure Measurement) Trial.
Frank Ruschitzka,Jeffrey S. Borer,Henry Krum,Andreas J. Flammer,Neville D. Yeomans,Peter Libby,Thomas F. Lüscher,Daniel H. Solomon,M. Elaine Husni,David Y. Graham,Deborah A Davey,Lisa Wisniewski,Venu Menon,Rana Fayyad,Bruce Beckerman,Dinu Iorga,A. Michael Lincoff,Steven E. Nissen +17 more
TL;DR: Allocation to the non-selective NSAID ibuprofen, compared with the COX-2 selective inhibitor celecoxib was associated with a significant increase of SBP, and a higher incidence of new-onset hypertension.