T
Thomas F. Lüscher
Researcher at University of Zurich
Publications - 1613
Citations - 88517
Thomas F. Lüscher is an academic researcher from University of Zurich. The author has contributed to research in topics: Endothelium & Myocardial infarction. The author has an hindex of 134, co-authored 1560 publications receiving 79034 citations. Previous affiliations of Thomas F. Lüscher include University of Texas Southwestern Medical Center & Durham University.
Papers
More filters
Journal ArticleDOI
Structure and Function of the Rat Basilar Artery During Chronic Nitric Oxide Synthase Inhibition
Pierre Moreau,Hiroyuki Takase,Christoph F. Küng,Menno-M. van Rooijen,Thomas Schaffner,Thomas F. Lüscher +5 more
TL;DR: The remodeling and functional alterations of the basilar artery seem to depend mainly on the elevation of arterial pressure with little contribution of the L-arginine pathway, and nitric oxide does not seem to be implicated in the modulation of normal cerebral vascular growth in vivo.
Journal ArticleDOI
Effects of atrial pacing on arterial and coronary sinus endothelin-1 levels in syndrome X
Gaetano Antonio Lanza,Thomas F. Lüscher,Vincenzo Pasceri,Sidney Shaw,Antonino Buffon,A. S. Montenero,Filippo Crea,Attilio Maseri +7 more
TL;DR: The findings suggest that an increased vasoconstrictor activity of microvascular endothelium is present in at least some patients with syndrome X and may be involved in the pathogenesis of the syndrome.
Journal ArticleDOI
ECG-gated multi-detector row CT for assessment of mitral valve disease: initial experience
Jürgen K. Willmann,Richard Kobza,Justus E. Roos,Mario Lachat,Rolf Jenni,Paul R. Hilfiker,Thomas F. Lüscher,Borut Marincek,Dominik Weishaupt +8 more
TL;DR: Contrast-enhanced, retrospectively ECG-gated MDCT allows good to excellent visualization of anatomical details of the mitral valve and its apparatus, and demonstrates good agreement with echocardiography and surgery in diagnosing mitral valves abnormalities.
Journal ArticleDOI
Obesity-induced activation of JunD promotes myocardial lipid accumulation and metabolic cardiomyopathy
Sarah Costantino,Alexander Akhmedov,Giovanni Melina,Shafeeq A. Mohammed,Alaa Othman,Samuele Ambrosini,Winandus J Wijnen,Lidia Sada,Giuseppino M. Ciavarella,Luca Liberale,Luca Liberale,Felix C. Tanner,Christian M. Matter,Thorsten Hornemann,Massimo Volpe,Fatima Mechta-Grigoriou,Fatima Mechta-Grigoriou,Giovanni G. Camici,Riccardo Sinatra,Thomas F. Lüscher,Thomas F. Lüscher,Francesco Paneni +21 more
TL;DR: The role of Activator Protein 1 (AP-1) member JunD was recently identified as a key modulator of hepatic lipid metabolism in obese mice, and the role of JunD in obesity-induced MC was investigated in this paper.
Journal ArticleDOI
Nitric-oxide-mediated relaxations in salt-induced hypertension: Effect of chronic β1-selective receptor blockade
Francesco Cosentino,Sandro Bonetti,Rudolf Rehorik,Masato Eto,Gabriele Werner-Felmayer,Massimo Volpe,Thomas F. Lüscher +6 more
TL;DR: It is demonstrated for the first time that the acute NO-mediated vasodilatory action of nebivolol is also present during chronic treatment, and might become a new therapeutic tool with which to exert vascular protective effects against end-organ damage in conditions associated with NO deficiency.