T
Thomas F. Lüscher
Researcher at University of Zurich
Publications - 1613
Citations - 88517
Thomas F. Lüscher is an academic researcher from University of Zurich. The author has contributed to research in topics: Endothelium & Myocardial infarction. The author has an hindex of 134, co-authored 1560 publications receiving 79034 citations. Previous affiliations of Thomas F. Lüscher include University of Texas Southwestern Medical Center & Durham University.
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Journal ArticleDOI
Prothrombotic Gene Expression Profile in Vascular Smooth Muscle Cells of Human Saphenous Vein, but Not Internal Mammary Artery
Sravan Payeli,R. Latini,Catherine Gebhard,A. Patrignani,U. Wagner,Thomas F. Lüscher,Felix C. Tanner +6 more
TL;DR: Among the genes of the coagulation system, TF and tPA are differentially expressed in VSMCs from IMA versus SV, consistent with protection of IMA from thrombus formation and vascular remodeling.
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Amphetamines induce tissue factor and impair tissue factor pathway inhibitor: role of dopamine receptor type 4.
Catherine Gebhard,Alexander Breitenstein,Alexander Akhmedov,Caroline E. Gebhard,Giovanni G. Camici,Thomas F. Lüscher,Felix C. Tanner +6 more
TL;DR: Amphetamines induce endothelial TF expression via stimulation of dopamine D4 receptor and activation of the MAPKs p38 and ERK and may account for the increased incidence of acute vascular syndromes after amphetamine consumption.
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Endothelin A Receptor Antagonists in Congestive Heart Failure: Blocking the Beast while Leaving the Beauty Untouched?
TL;DR: Results indicate that ET receptor antagonists indeed have a potential to improve hemodynamics, symptoms, and potentially prognosis of CHF which still carries a high mortality.
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Medical Misinformation: Vet the Message!
Joseph A. Hill,Stefan Agewall,Adrian Baranchuk,George W. Booz,Jeffrey S. Borer,Paolo G. Camici,Peng Sheng Chen,Anna F. Dominiczak,Çetin Erol,Cindy L. Grines,Robert J. Gropler,Tomasz J. Guzik,Markus K. Heinemann,Ami E. Iskandrian,Bradley P. Knight,Barry London,Thomas F. Lüscher,Marco Metra,Kiran Musunuru,Brahmajee K. Nallamothu,Andrea Natale,Sanjeev Saksena,Michael H. Picard,Sunil V. Rao,Willem J. Remme,Robert S. Rosenson,Nancy K. Sweitzer,Adam Timmis,Christiaan Vrints +28 more
TL;DR: “Mrs.
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Expression and activity patterns of nitric oxide synthases and antioxidant enzymes reveal a substantial heterogeneity between cardiac and vascular aging in the rat.
Bernd van der Loo,Markus Bachschmid,Ralf Labugger,Stefan Schildknecht,Juliane Kilo,Raphael Hahn,Miriam Palacios-Callender,Thomas F. Lüscher +7 more
TL;DR: Changes in the aged myocardium with respect to enzymes crucially involved in maintaining the redox homeostasis, seem to be much less pronounced or even absent compared to the vascular aging process, which may point to heterogeneity in the molecular regulation of the cardiovascular aging process.