Toshio Suda

TL;DR: Flow cytometric analysis revealed that this population is composed of Plzf-positive cells and exhibits quiescence and the side population phenotype, fulfilling general stem cell criteria, and ATM plays an essential role in maintenance of undifferentiated spermatogonia and their stem cell capacity by suppressing DNA damage-induced cell-cycle arrest.

TL;DR: It is shown that the seven-transmembrane-region receptor dendritic cell-specific trans Membrane protein (DC-STAMP) is required for cell–cell fusion of osteoclasts and foreign body giant cells.

TL;DR: It is observed that angiopoietin-1 plays a substantial role in the formation of the retinal vascular network during postnatal development and that Ang1 supplementation can rescue vascular retinopathies by simultaneously promoting healthy vascular network formation and inhibiting subsequent abnormal angiogenesis, vascular leakage, and neuronal dysfunction in the retinas of the OIR model.

TL;DR: Atm-mediated ROS regulation is essential for proper DNA recombination, preventing immunodeficiency, and lymphomagenesis, and in vivo administration of NAC to Atm−/− mice restored normal T cell development and inhibited aberrant V(D)J recombination.

TL;DR: Observations suggest that GM-CSF, as well as IL-3, should play an important role in megakaryocytopoiesis.