T
Traci L. Bricker
Researcher at Washington University in St. Louis
Publications - 34
Citations - 2597
Traci L. Bricker is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Medicine & Virus. The author has an hindex of 13, co-authored 24 publications receiving 1792 citations.
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Journal ArticleDOI
Immunosuppression in patients who die of sepsis and multiple organ failure.
Jonathan S. Boomer,Kathleen To,Kathy Chang,Osamu Takasu,Dale F. Osborne,Andrew H. Walton,Traci L. Bricker,Stephen D. Jarman,Daniel Kreisel,Alexander S. Krupnick,Anil Srivastava,Paul E. Swanson,Jonathan Green,Richard S. Hotchkiss +13 more
TL;DR: Patients who die in the ICU following sepsis compared with patients who die of nonsepsis etiologies have biochemical, flow cytometric, and immunohistochemical findings consistent with immunosuppression, and targeted immune-enhancing therapy may be a valid approach in selected patients with sepsi.
Journal ArticleDOI
Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure
Jonathan S. Boomer,Kathleen To,Kathy Chang,Osamu Takasu,Dale F. Osborne,Andrew H. Walton,Traci L. Bricker,Stephen D. Jarman,Daniel Kreisel,Alexander S. Krupnick,Anil Srivastava,Paul E. Swanson,Jonathan Green,Richard S. Hotchkiss +13 more
TL;DR: In this article, rapid postmortem spleen and lung tissue harvest was performed at the bedsides of 40 patients who died in intensive care units (ICUs) of academic medical centers with active severe sepsis to characterize their immune status at the time of death (2009-2011).
Journal ArticleDOI
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains.
Rita E. Chen,Emma S. Winkler,James Brett Case,Ishmael D. Aziati,Traci L. Bricker,Astha Joshi,Tamarand L. Darling,Baoling Ying,John M. Errico,Swathi Shrihari,Laura A. VanBlargan,Xuping Xie,Pavlo Gilchuk,Seth J. Zost,Lindsay Droit,Zhuoming Liu,Spencer Stumpf,David Wang,Scott A. Handley,W. Blaine Stine,Pei Yong Shi,Meredith E. Davis-Gardner,Mehul S. Suthar,Miguel Garcia Knight,Raul Andino,Charles Y. Chiu,Ali H. Ellebedy,Daved H. Fremont,Sean P. J. Whelan,James E. Crowe,Lisa A. Purcell,Davide Corti,Adrianus C. M. Boon,Michael S. Diamond +33 more
TL;DR: In this paper, the authors report the in vitro and in vivo activity of a panel of monoclonal antibodies (mAbs) against SARS-CoV-2 variant viruses, which correspond to many mAb combinations in advanced clinical development by Vir Biotechnology, AbbVie, AstraZeneca, Regeneron and Lilly.
Journal ArticleDOI
Defining the risk of SARS-CoV-2 variants on immune protection
Marciela M. DeGrace,Elodie Ghedin,Matthew B. Frieman,Florian Krammer,Alba Grifoni,Arghavan Alisoltani,Galit Alter,Rama Rao Amara,Ralph S. Baric,Dan H. Barouch,Jesse D. Bloom,Louis-Marie Bloyet,Gaston Bonenfant,Adrianus C. M. Boon,Eli Boritz,Debbie L Bratt,Traci L. Bricker,Liliana L Brown,William Buchser,Juan Manuel Carreño,Liel Cohen-Lavi,Tamarand L. Darling,Meredith E. Davis-Gardner,Bethany L. Dearlove,Han Di,Meike Dittmann,Nicole A. Doria-Rose,Daniel C. Douek,Christian Drosten,Venkata Viswanadh Edara,Ali H. Ellebedy,Thomas P. Fabrizio,Guido Ferrari,William C. Florence,Ron A. M. Fouchier,John Franks,Adolfo García-Sastre,Adam Godzik,Ana S. Gonzalez-Reiche,Aubree Gordon,Bart L. Haagmans,Peter Halfmann,David D. Ho,Michael R. Holbrook,Yaoxing Huang,Sarah James,Lukasz Jaroszewski,Trushar Jeevan,Robert M. Johnson,Terry Jones,Astha Joshi,Yoshihiro Kawaoka,Lisa Kercher,Marion Koopmans,Bette T. Korber,Eilay Koren,Richard A. Koup,Eric B. LeGresley,Jacob E. Lemieux,Mariel J. Liebeskind,Zhuoming Li,Brandi Livingston,James Logue,Yang Luo,Adrian B. McDermott,M. Juliana McElrath,Victoria A. Meliopoulos,Vineet D. Menachery,David C. Montefiori,Barbara Mühlemann,Vincent J. Munster,Jennifer E. Munt,Manoj S. Nair,Antonia Netzl,Anna Maria Niewiadomska,Sijy O'Dell,Andrew Pekosz,Stanley Perlman,Marjorie Cornejo Pontelli,Barry Rockx,Morgane Rolland,Paul W. Rothlauf,Sinai Sacharen,Richard H. Scheuermann,R. Schmidt,Michael Schotsaert,Stacey Schultz-Cherry,Robert A. Seder,Mayya Sedova,Alessandro Sette,Reed S. Shabman,Xiaoying Shen,Pei Yong Shi,Maulik Shukla,Viviana Simon,Spencer Stumpf,Nancy J. Sullivan,Larissa B. Thackray,James Theiler,Paul G. Thomas,Sanja Trifkovic,Sina Türeli,Samuel Ashby Turner,Maria Vakaki,Harm van Bakel,Laura A. VanBlargan,Leah R. Vincent,Zachary S. Wallace,Liang Wang,Maple Wang,Pengfei Wang,Wei Wang,Scott C. Weaver,Richard J. Webby,Carol D. Weiss,David E. Wentworth,Stuart Weston,Sean P. J. Whelan,Bradley M. Whitener,S. H. Wilks,Xuping Xie,Baoling Ying,Hyejin Yoon,Bin Zhou,Tomer Hertz,Derek J. Smith,Michael S. Diamond,Diane J. Post,Mehul S. Suthar +128 more
TL;DR: The SARS-CoV-2 Assessment of Viral Evolution (SAVE) as mentioned in this paper was designed to provide a real-time risk assessment of SARS CoV2 variants that could potentially affect the transmission, virulence and resistance to infection-and vaccine-induced immunity.
Journal ArticleDOI
Cutting Edge: B and T Lymphocyte Attenuator and Programmed Death Receptor-1 Inhibitory Receptors Are Required for Termination of Acute Allergic Airway Inflammation
Christine M. Deppong,Twyla I. Juehne,Michelle A. Hurchla,Lindzy D. Friend,Dulari D. Shah,Christine M. Rose,Traci L. Bricker,Laurie P. Shornick,Erika C. Crouch,Theresa L. Murphy,Michael J. Holtzman,Kenneth M. Murphy,Jonathan M. Green +12 more
TL;DR: These receptors are critical determinants of the duration of allergic airway inflammation and there is a temporally regulated expression of both the receptors and their ligands during the course of allergicAirway inflammation.