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Travis N. Mavrich

Researcher at University of Pittsburgh

Publications -  12
Citations -  668

Travis N. Mavrich is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Lysogenic cycle & Bacteriophage. The author has an hindex of 9, co-authored 12 publications receiving 407 citations. Previous affiliations of Travis N. Mavrich include University College Cork.

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Prophage-mediated defence against viral attack and viral counter-defence.

TL;DR: Characterization of ten Cluster N temperate mycobacteriophages revealed at least five distinct prophage-expressed viral defence systems that interfere with the infection of lytic and temperate phages that are either closely related (homotypic defence) or unrelated (heterotypic Defence) to the prophages.
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Bacteriophage evolution differs by host, lifestyle and genome.

TL;DR: It is shown that bacteriophages evolve within two general evolutionary modes that differ in the extent of horizontal gene transfer by an order of magnitude, suggesting there are genetic as well as ecological drivers of vertical gene transfer rates.
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Bacteriophages of Gordonia spp. Display a Spectrum of Diversity and Genetic Relationships.

TL;DR: It is suggested that any barriers to genetic exchange are soft and readily violable, and further isolation and genomic comparison of phages targeted at related groups of hosts promise to reveal pathways of bacteriophage evolution.
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Evolution of Superinfection Immunity in Cluster A Mycobacteriophages

TL;DR: It is shown that phages with mesotypic (i.e., genetically related but distinct) immunity systems exhibit asymmetric and incomplete superinfection phenotypes, and mutations conferring escape from homotypic or mes prototypic immunity have various escape specificities.
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Genomic Diversity of Bacteriophages Infecting Microbacterium SPP

Deborah Jacobs-Sera, +54 more
- 18 Jun 2020 - 
TL;DR: The isolation and genomic characterization of 116 phages that infect Microbacterium spp.