U
Udo Stenzel
Researcher at Max Planck Society
Publications - 24
Citations - 12077
Udo Stenzel is an academic researcher from Max Planck Society. The author has contributed to research in topics: Ancient DNA & Genome. The author has an hindex of 21, co-authored 24 publications receiving 10823 citations.
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Journal ArticleDOI
A Draft Sequence of the Neandertal Genome
Richard E. Green,Johannes Krause,Adrian W. Briggs,Tomislav Maricic,Udo Stenzel,Martin Kircher,Nick Patterson,Heng Li,Weiwei Zhai,Markus Hsi-Yang Fritz,Nancy F. Hansen,Eric Durand,Anna-Sapfo Malaspinas,Jeffrey D. Jensen,Tomas Marques-Bonet,Tomas Marques-Bonet,Can Alkan,Kay Prüfer,Matthias Meyer,Hernán A. Burbano,Jeffrey M. Good,Jeffrey M. Good,Rigo Schultz,Ayinuer Aximu-Petri,Anne Butthof,Barbara Höber,Barbara Höffner,Madien Siegemund,Antje Weihmann,Chad Nusbaum,Eric S. Lander,Carsten Russ,Nathaniel Novod,Jason P. Affourtit,Michael Egholm,Christine Verna,Pavao Rudan,Dejana Brajković,Željko Kućan,Ivan Gušić,Vladimir B. Doronichev,Liubov V. Golovanova,Carles Lalueza-Fox,Marco de la Rasilla,Javier Fortea,Antonio Rosas,Ralf Schmitz,Philip L. F. Johnson,Evan E. Eichler,Daniel Falush,Ewan Birney,James C. Mullikin,Montgomery Slatkin,Rasmus Nielsen,Janet Kelso,Michael Lachmann,David Reich,David Reich,Svante Pääbo +58 more
TL;DR: The genomic data suggest that Neandertals mixed with modern human ancestors some 120,000 years ago, leaving traces of Ne andertal DNA in contemporary humans, suggesting that gene flow from Neand Bertals into the ancestors of non-Africans occurred before the divergence of Eurasian groups from each other.
Journal ArticleDOI
A high-coverage genome sequence from an archaic Denisovan individual
Matthias Meyer,Martin Kircher,Marie Theres Gansauge,Heng Li,Fernando Racimo,Swapan Mallick,Swapan Mallick,Joshua G. Schraiber,Flora Jay,Kay Prüfer,Cesare de Filippo,Peter H. Sudmant,Can Alkan,Can Alkan,Qiaomei Fu,Qiaomei Fu,Ron Do,Nadin Rohland,Nadin Rohland,Arti Tandon,Arti Tandon,Michael Siebauer,Richard E. Green,Katarzyna Bryc,Adrian W. Briggs,Udo Stenzel,Jesse Dabney,Jay Shendure,Jacob O. Kitzman,Michael F. Hammer,Michael V. Shunkov,A.P. Derevianko,Nick Patterson,Aida M. Andrés,Evan E. Eichler,Evan E. Eichler,Montgomery Slatkin,David Reich,David Reich,Janet Kelso,Svante Pääbo +40 more
TL;DR: The genomic sequence provides evidence for very low rates of heterozygosity in the Denisova, probably not because of recent inbreeding, but instead because of a small population size, and illuminates the relationships between humans and archaics, including Neandertals, and establishes a catalog of genetic changes within the human lineage.
Journal ArticleDOI
Genetic history of an archaic hominin group from Denisova Cave in Siberia
David Reich,Richard E. Green,Martin Kircher,Johannes Krause,Nick Patterson,Eric Durand,Bence Viola,Adrian W. Briggs,Udo Stenzel,Philip L. F. Johnson,Tomislav Maricic,Jeffrey M. Good,Tomas Marques-Bonet,Tomas Marques-Bonet,Can Alkan,Qiaomei Fu,Swapan Mallick,Swapan Mallick,Heng Li,Matthias Meyer,Evan E. Eichler,Mark Stoneking,Michael P. Richards,Sahra Talamo,Michael V. Shunkov,A.P. Derevianko,Jean-Jacques Hublin,Janet Kelso,Montgomery Slatkin,Svante Pääbo +29 more
TL;DR: A tooth found in Denisova Cave carries a mitochondrial genome highly similar to that of the finger bone, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans.
Journal ArticleDOI
Patterns of damage in genomic DNA sequences from a Neandertal
Adrian W. Briggs,Udo Stenzel,Philip L. F. Johnson,Richard E. Green,Janet Kelso,Kay Prüfer,Matthias Meyer,Johannes Krause,Michael T. Ronan,Michael Lachmann,Svante Pääbo +10 more
TL;DR: DNA sequences determined from a Neandertal, a mammoth, and a cave bear show that purines are overrepresented at positions adjacent to the breaks in the ancient DNA, suggesting that depurination has contributed to its degradation.
Journal ArticleDOI
A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing
Richard E. Green,Anna-Sapfo Malaspinas,Johannes Krause,Adrian W. Briggs,Philip L. F. Johnson,Caroline Uhler,Matthias Meyer,Jeffrey M. Good,Tomislav Maricic,Udo Stenzel,Kay Prüfer,Michael Siebauer,Hernán A. Burbano,Michael T. Ronan,Jonathan M. Rothberg,Michael Egholm,Pavao Rudan,Dejana Brajković,Zeljko Kucan,Ivan Gušić,Mårten Wikström,Liisa Laakkonen,Janet Kelso,Montgomery Slatkin,Svante Pääbo +24 more
TL;DR: Analysis of the assembled sequence unequivocally establishes that the Neandertal mtDNA falls outside the variation of extant human mtDNAs, and allows an estimate of the divergence date between the two mtDNA lineages of 660,000 +/- 140,000 years.