Valeria Specchia

TL;DR: It is shown that YAP/TAZ activity is controlled by the SREBP/mevalonate pathway, which is required for proliferation and self-renewal of breast cancer cells and reveals an additional layer of YAP-TAZ regulation by metabolic cues.

TL;DR: The main advantages and pitfalls of metabarcoding approaches to assess parameters such as richness, abundance, taxonomic composition and species ecological values, to be used for calculation of biotic indices are discussed.

TL;DR: It is shown that, in Drosophila, functional alterations of Hsp90 affect the Piwi-interacting RNA (piRNA; a class of germ-line-specific small RNAs) silencing mechanism leading to transposon activation and the induction of morphological mutants, which indicates that Hsp 90 mutations can generate new variation by transposOn-mediated ‘canonical’ mutagenesis.

TL;DR: Several possible implications about environmental stress, transposon, and evolution are discussed offering also a support to the concept of evolvability.

TL;DR: How the multifaceted roles of the FMRP protein have been addressed in the Drosophila model is explored and how the gained knowledge may open novel perspectives for understanding the molecular defects causing the disease and for identifying novel therapeutical targets are explored.