Wen-Cai Ye

TL;DR: A putative biosynthetic pathway toward callisretones A and B involving the rearrangement of the terpenoid motif is proposed and showed inhibitory effects on nitric oxide production.

TL;DR: A new prenylcoumarin, 5-methoxyl-4,2′-epoxy-3-(4′, 5′-dihydroxyphenyl)-linear pyranocou marin, and a new flavonoid, 3-acetyl-3,5,4′-trihydroxy-7- methoxylflavone, were isolated from the roots of Ficus hirta.

TL;DR: First insights into the stereoselective inhibition of NKA by bufadienolides highlight the important role of the hydrophilic moieties at C3 for binding, and may explain why only 3β-hydroxylated bufadiensolides are present as a toxic chemical defence in toad venom.

TL;DR: Behavioral studies indicate that anemoside A3 not only facilitates hippocampal long-term potentiation but also enhances spatial reference memory formation in mice, suggesting that AA3 is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative diseases.

TL;DR: Five monoterpenoid bisindole alkaloids with new carbon skeletons, gelsecorydines A-E (1-5), together with their biogenetic precursors were isolated from the fruits of Gelsemium elegans and a plausible biosynthetic pathway for compounds 1-5 is proposed.