Wen-Cai Ye

TL;DR: Four new sesquiterpene quinones possessing the unprecedented "dysidavarane" carbon skeleton were isolated from the South China Sea sponge Dysidea avara and their cytotoxic activity against four human cancer cell lines and PTP1B inhibitory activity were evaluated.

TL;DR: Saxifragifolin D inhibits breast cancer cell growth and induces interplay between apoptosis and autophagy through ROS-mediated endoplasmic reticulum stress.

TL;DR: The ethanolic extract from the fruits of Chenopodium album L. (FCAL), orally administered at doses of 100-400 mg/kg, dose-dependently inhibited scratching behavior induced by 5-HT or compound 48/80 in mice and significantly attenuated the writhing responses induced by an intraperitoneal injection of acetic acid and the inflammatory pain response induced by a intraplantar injection of formalin in mice.

TL;DR: It is shown that arenobufagin inhibited vascular endothelial growth factor (VEGF)-induced viability, migration, invasion and tube formation in human umbilical vein endothelial cells (HUVECs) in vitro and blocked angiogenesis in an ex vivo model.

TL;DR: Five sesquiterpene-based meroterpenoids with three kinds of new skeletons, isolated from the leaves of Myrtus communis, featured a new carbon skeleton with an unprecedented octahydrospiro[bicyclo[7.0]undecane-2,2'-chromene] tetracyclic ring system.