Wen-Cai Ye

TL;DR: A novel reactive probe is described, 3-phenyl-2H-azirine, that enables chemoselective modification of carboxyl groups in proteins under both in vitro and in situ conditions with excellent efficiency.

TL;DR: Amaryllidaceae alkaloids inhibit nuclear‐to‐cytoplasmic export of ribonucleoprotein (RNP) complex of highly pathogenic avian influenza virus H5N1.

TL;DR: This study is the first to report the efficacy of ailanthones against Huh7 cells and to elucidate its underlying molecular mechanisms, suggesting that ailanthone is a potential agent for the treatment of liver cancer.

TL;DR: The first monoterpene-based meroterpenoid and two novel sesquiterpenes-based ones with unprecedented skeletons were isolated from the leaves of Psidium guajava and their structures with absolute configuration were elucidated by extensive spectroscopic studies.

TL;DR: This study identifies that Dock4 is critical for neurite differentiation and extension in neuroblastoma cells and hippocampal neurons and reveals that the SH3 domain-mediated interaction of Dock 4 is required for its activity toward neurites differentiation, whereas its proline-rich C terminus is not essential for this regulation.