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Yong-Bin Yan
Researcher at Tsinghua University
Publications - 118
Citations - 3179
Yong-Bin Yan is an academic researcher from Tsinghua University. The author has contributed to research in topics: Crystallin & Protein aggregation. The author has an hindex of 28, co-authored 117 publications receiving 2765 citations. Previous affiliations of Yong-Bin Yan include Fourth Military Medical University.
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Journal ArticleDOI
Lanosterol reverses protein aggregation in cataracts
Ling Zhao,Xiang-Jun Chen,Jie Zhu,Yi-Bo Xi,Xu Yang,Li-Dan Hu,Hong Ouyang,Sherrina Patel,Xin Jin,Danni Lin,Frances Wu,Ken Flagg,Huimin Cai,Gen Li,Guiqun Cao,Ying Lin,Daniel Chen,Cindy Wen,Christopher Chung,Yandong Wang,Austin Qiu,Emily Yeh,Wenqiu Wang,Xun Hu,Seanna Grob,Ruben Abagyan,Zhiguang Su,Harry C. Tjondro,Xi-Juan Zhao,Hongrong Luo,Rui Hou,J. Jefferson,P. Perry,Weiwei Gao,Igor Kozak,David B. Granet,Yingrui Li,Xiaodong Sun,Jun Wang,Liangfang Zhang,Yizhi Liu,Yong-Bin Yan,Kang Zhang +42 more
TL;DR: In this paper, the authors identify two distinct homozygous LSS missense mutations (W581R and G588S) in two families with extensive congenital cataracts.
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Regulating the drought-responsive element (DRE)-mediated signaling pathway by synergic functions of trans-active and trans-inactive DRE binding factors in Brassica napus.
TL;DR: The results hereby provide a new insight into the regulation mechanisms of the DRE-mediated signaling pathway in response to cold stress and suggest that the trans-active Group I DREBs were expressed at the early stage of cold stress to open the D RE-mediated signaled pathway in cold stress, whereas theTrans-inactive Group II D REBs were expression at the later stage to close the signal pathway in a competitive manner.
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Structural Analysis of Pseudomonas syringae AvrPtoB Bound to Host BAK1 Reveals Two Similar Kinase-Interacting Domains in a Type III Effector
Wei Cheng,Kathy R. Munkvold,Haishan Gao,Johannes Mathieu,Simon Schwizer,Sha Wang,Yong-Bin Yan,Jinjing Wang,Gregory B. Martin,Gregory B. Martin,Gregory B. Martin,Jijie Chai +11 more
TL;DR: The crystal structure of the AvrPtoB-BAK1 complex was reported, which revealed structural similarity between these two AvrptoB domains, suggesting that they arose by intragenic duplication, shedding light on a structural mechanism underlying host-pathogen coevolution.
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Protein thermal aggregation involves distinct regions: sequential events in the heat-induced unfolding and aggregation of hemoglobin.
TL;DR: The sequential events occurring during thermal unfolding and aggregation process of hemoglobin were studied by two-dimensional infrared correlation spectroscopy and suggested that protein thermal aggregation involves distinct regions.
Journal ArticleDOI
The conserved Ala37 in the ERF/AP2 domain is essential for binding with the DRE element and the GCC box
TL;DR: Results suggested that Ala37 might play a crucial role in the DNA binding or the stability of the ERF/AP2 domain.