Chittagong Medical College Hospital

About: Chittagong Medical College Hospital is a healthcare organization based out in Chittagong, Bangladesh. It is known for research contribution in the topics: Population & Malaria. The organization has 676 authors who have published 601 publications receiving 7040 citations.

Divergences in Clinical, Anthropometric, Metabolic, and Hormonal Parameters among Different Phenotypes of Polycystic Ovary Syndrome Presenting at Endocrinology Outpatient Departments: A Multicenter Study from Bangladesh

Abstract: Background: Polycystic ovary syndrome (PCOS) is a heterogeneous androgen-excess disorder. Data comparing the PCOS phenotypes in Bangladesh are scarce. Objectives: The objective of this study was to find out the distribution of Rotterdam classified PCOS phenotypes and to compare the phenotypes concerning clinical, anthropometric, metabolic, and hormonal parameters. Subjects and Methods: In this cross-sectional study, 370 PCOS cases in the age group of 20–45 years diagnosed by the Rotterdam consensus criteria were recruited from the endocrinology outpatient departments of several tertiary hospitals of Bangladesh. Metabolic syndrome (MetS) was diagnosed using the International Diabetes Federation criteria. Results: The prevalence of phenotypes A, B, C, and D were 59.2%, 14.1%, 11.9%, and 14.9%, respectively. More than one-third (34.6%) of the women had pre-hypertension (pre-HTN)/hypertension (HTN), 34.1% had abnormal glucose intolerance (AGT), 93.0% had dyslipidemia, and 57.0% had MetS. The hyperandrogenic phenotypes (A, B, and C) had higher prevalence of pre-HTN/HTN, AGT, dyslipidemia, and MetS compared to the normoandrogenic phenotype D, though the differences were statistically insignificant. The clinical and biochemical markers of hyperandrogenism (Ferriman-Gallwey score, hirsutism, acne, and serum testosterone levels) did not differ among the hyperandrogenic phenotypes. The serum prolactin level was highest in phenotype C. No differences were observed in most other clinical, anthropometric, metabolic, and hormonal parameters among the four phenotypes. Conclusion: Phenotype A is the most prevalent phenotype of PCOS in our setting. The prevalence of MetS was considerably high. Most of the clinical, anthropometric, and metabolic parameters were similar across the four PCOS phenotypes in this study.

Musculoskeletal Consequences of Systemic Corticosteroid Misuse in a Patient with Psoriasis

Abstract: This is a case history of a patient with psoriasis with indiscriminate systemic corticosteroid use for a prolonged period. A single patient can be victim of multiple deleterious effects of corticosteroids. The aim of this case discussion is not only to describe the myriads of sequels of corticosteroid misuse effecting musculoskeletal system severely but simultaneously to rethink about prescription of steroid in psoriasis, too. Chatt Maa Shi Hosp Med Coll J; Vol.14 (2); Jul 2015; Page 80-82

Early Experience of Spinal Instrumentation at NITOR, Dhaka "Spinal Stabilization is the Goal for Early Mobilization"

Abstract: In our country spinal injury patients are mostly treated conservatively for 12 to 18 weeks. So complications of immobilization for long time are more (bed sore, UTI, respiratory infection, paralytic ilius, wt. loss and lastly psychological distress).With this in our mind spinal stabilization was done for early mobilization of the paraplegic patients to prevent complications of immobilization. Objective of this study were: to reduce pain, to early mobilize for prevention of complications of immobilization and to assess the improvement after spinal stabilization. This Randomized prospective study was conducted from May 2003 to January 2004 at Tertiary referral Orthopaedic Institute. DOI: 10.3329/bmj.v38i1.3581 Bangladesh Medical Journal 38(1) 2009 15-17

Superior ankyloglossia syndrome

Abstract: We report a rare case of superior ankyloglossia syndrome in a male neonate who had palatoglossal adhesion, cleft palate, patent ductus arteriosus, penile chordee without hypospadias and penoscrotal transposition. He also had superior labial frenulum and posterior ankyloglossia. The mother had bad obstetric history, developed per vaginal bleeding during pregnancy and used progesterone. The palatoglossal adhesion was divided with bipolar diathermy under intravenous anaesthesia at 7th day of life and he awaits repair of other defects.

Multi System Involvement due to Acute Methanol Toxicity in a Young Male

Abstract: A young male who had history of ingestion of methanol developed severe anorexia, nausea, and profuse vomiting after a short period. After evaluation he was found to develop severe renal failure, metabolic acidosis & dyselectrolemia. He was given haemodialysis for several sessions. Few days later he developed weakness and blurred vision. Neurological evaluation showed toxic neuropathy. In spite of giving haemodialysis near about three months his renal function did not improved. Renal biopsy showed features suggestive of acute cortical necrosis. He was declared a case of End Stage Renal Disease (ESRD) & an arterio-venus fistula was created in his left forearm for maintenance of haemodialysis DOI: http://dx.doi.org/10.3329/bja.v11i1.20508 Bangladesh Journal of Anatomy, January 2013, Vol. 11 No. 1 pp 44-47