Institution
Dalian Medical University
Education•Dalian, China•
About: Dalian Medical University is a education organization based out in Dalian, China. It is known for research contribution in the topics: Cancer & Apoptosis. The organization has 15623 authors who have published 9993 publications receiving 164145 citations.
Topics: Cancer, Apoptosis, Cell growth, Metastasis, PI3K/AKT/mTOR pathway
Papers published on a yearly basis
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TL;DR: The data suggest the importance of STAT3 signaling in maintenance and survival of medulloblastoma cells and suggest that this signaling may be the major target of resveratrol.
85 citations
TL;DR: Blood GSH levels and urinary 8-OHdG concentrations of arsenic-exposed children and adults showed strong associations with the levels of urinary arsenic species, and associations of arsenic methylation capacity with 8- OHdG, GSH and SOD were observed in multivariate regression analyses.
85 citations
TL;DR: Thinning of the bone trabeculae holding dental implants may occur with estrogen deficiency, and both the bone volume and implant-bone contact were significantly decreased in the cancellous bone area in ovariectomized rats compared with the sham-operated rats.
85 citations
TL;DR: Findings suggest that APS can activate macrophages to release NO and TNF-α, which directly blocks cancer cell growth, and the anti-breast cancer effect of APS and the in vivo mechanism will be further elucidated with a review to provide a therapeutic strategy for breast cancer.
85 citations
TL;DR: Fluorescence co-localization studies reveal that DBT is a mitochondria-targetable fluorescent probe that has potential application for exploring the role played by SO 2 derivatives in biology.
Abstract: A fluorescent probe ( DBT ) based on conjugation of 2,3-dimethylbenzo[ d ]thiazol-3-ium iodide to 3-(benzo[ d ]thiazol-2-yl)-2-hydroxy-5-methylbenzaldehyde for the detection of sulfur dioxide derivatives (HSO 3 − /SO 3 2− ) has been developed. DBT exhibits highly selective colorimetric and ratiometric fluorescence dual response to HSO 3 − with a fluorescence detection limit of 3.50 × 10 −7 M. The HSO 3 − sensing mechanism was confirmed to undergo nucleophilic addition of HSO 3 − to alkene double bond of DBT as evidenced by 1 H NMR and HRMS analysis. The probe is MCF-7 cell permeable and applicable for fluorescence imaging of exogenous and intrinsically generated intracellular SO 2 derivatives in the living cells. Fluorescence co-localization studies reveal that DBT is a mitochondria-targetable fluorescent probe. Thus, DBT has potential application for exploring the role played by SO 2 derivatives in biology.
85 citations
Authors
Showing all 15657 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Jing Wang | 184 | 4046 | 202769 |
| Jan-Åke Gustafsson | 147 | 1058 | 98804 |
| Melitta Schachner | 135 | 861 | 67304 |
| Yan Zhang | 107 | 2410 | 57758 |
| Jau-Shyong Hong | 93 | 474 | 37172 |
| Li Zhang | 92 | 918 | 35648 |
| Charles G. Eberhart | 84 | 444 | 29920 |
| Ying Lu | 83 | 343 | 24913 |
| You-Lin Qiao | 78 | 595 | 23919 |
| Wei Wei | 75 | 1068 | 29415 |
| Weidong Le | 74 | 287 | 22551 |
| Jin-Tai Yu | 66 | 439 | 20020 |
| Wei Jiang | 65 | 660 | 18932 |
| Lan Tan | 62 | 387 | 13828 |
| Hua Li | 62 | 849 | 17933 |