King's College, Aberdeen

About: King's College, Aberdeen is a based out in . It is known for research contribution in the topics: Poison control & Sedimentary depositional environment. The organization has 712 authors who have published 918 publications receiving 25421 citations. The organization is also known as: King's College, Aberdeen & The University and King's College of Aberdeen.

Enhanced Differentiation of Human Embryonic Stem Cells Toward Definitive Endoderm on Ultrahigh Aspect Ratio Nanopillars

Abstract: Acknowledgements: C.H.R. and P.M.R. contributed equally to this work. The authors would like to thank the staff and technicians of the James Watt Nanofabrication Centre for their assistance during the substrate fabrication process – particularly Dr. Johnny Stormonth-Darling. C.H.R. and M.D. acknowledge financial support from Innovation Fund Denmark and Novo Nordisk A/S, Denmark. N.G. acknowledges funding from EPSRC (Engineering and Physical Sciences Research Council, BBSRC (Biotechnology and Biological Sciences Research Council), MRC (Medical Research Council), and the Royal Society. Further N.G. and P.M.R. acknowledge funding from the Engineering and Physical Sciences Research Council (EPSRC) Grant EP/F500424/1 DTC (Doctorial Training Centre) in Cell and Proteomic Technologies (PR), and EC-funded project NAPANIL (Contract No. FP7-CP-IP214249-2).

The Evolving Role of Constraints in the Functional Data Model

Abstract: We describe how to express constraints in a functional (semantic) data model, which has a working implementation in an object database. We trace the development of such constraints from being integrity checks embedded in procedural code to being something declarative and self-contained, combining data access and computation, that can be moved around into other contexts in intelligent distributed systems. We see this as paralleling and extending the original vision of functions as values in functional programming systems. It is greatly helped by using a referentially transparent functional formalisation. We illustrate these ideas by showing how constraints can move around within database systems (Colan & Angelic Daplex), being transformed for various uses, or even moved out into other systems and fused into a specification for a configuration problem. We look forward to future directions involving Agents.

Experimental study and mathematical modelling of a new of vibro-impact moling device

Abstract: In this paper experimental study and mathematical modelling of newly designed vibro-impact moling rig are presented. The design is based on electro-mechanical interactions of a conductor with an oscillating magnetic field. The rig consists of a metal bar placed within a solenoid which is connected to an RLC circuit, and an obstacle block positioned nearby. Both the solenoid and the block are attached to a base board. Externally supplied alternating voltage causes the bar to oscillate and hit the block resulting in the forward motion of the base board mimicking a mole penetration through the soil. By varying the excitation voltage and the capacitance in the circuit, a variety of system responses can be obtained. In the paper the rig design and experimental procedure are explained in detail, and the mathematical modelling of the rig is described. Then the obtained coupled electro-mechanical equations of motion are integrated numerically, and a comparison between experimental results and numerical predictions is presented.

Regional Fluid Flow and Gold Mineralization in the Dalradian of the Sperrin Mountains, Northern Ireland

Abstract: Gold vein mineralization occurs in the metamorphosed and deformed Dalradian (Neoproterozoic) rocks of the Sperrin Mountains, Northern Ireland. Two structures exerted a control on the location of the mineralization; the north-south Omagh lineament and the west-northwest-east-southeast Curraghinalt lateral ramp in the footwall of the northeast-southwest Omagh thrust. These are Caledonian structures resulting from the thrusting of Dalradian rocks over a possibly still active Ordovician arc. Cathodoluminescence microscopy distinguishes four phases of vein quartz in the Curraghinalt gold prospect. Fluid inclusion studies and stable isotope geochemistry have defined the probable fluids responsible for the precipitation of each quartz phase and associated sulfide and precious metal mineralization. The initial phase (Q1) appears to have been associated with the main Caledonian metamorphic event (ca. 470 Ma) and is nonauriferous. The second phase (Q2) forms an extensive cement to brecciated early quartz and is believed to have involved a fluid (~15 wt % CO 2 , 10 wt % NaCl + KCl equiv) with a significant magmatic component of 470 to 400 Ma, which underwent phase separation and dilution with a cooler formation water. This process resulted in precipitation of the main phase of gold mineralization characterized by an assemblage of electrum, pyrite, arsenopyrite, chalcopyrite, tennantite-tetrahedrite, and various tellurides. Similar fluids are observed on a regional scale, concentrated within the hanging wall of the Omagh thrust, indicating an extensive fluid-flow event. The relative abundance of gold at the Curraghinalt and Cavanacaw prospects is thought to be due to higher fluid fluxes in favorable zones of dilation and closer proximity to the fluid source. The deposit was subsequently reactivated with the precipitation of later quartz (Q3-Q4) from a formation water believed to be resident in the Dalradian metasediments, which mixed with a low-temperature, high-salinity basinal brine, probably during Carboniferous basin inversion. Brine flow resulted in the remobilization of earlier electrum, reducing its fineness, and also introduced base metal sulfides, carbonates, and barite. Again, brine flow is localized by the Omagh thrust, indicating the long-lived role of this structure in controlling regional fluid migration.