Institution
Leibniz Association
Government•Berlin, Germany•
About: Leibniz Association is a government organization based out in Berlin, Germany. It is known for research contribution in the topics: Population & Gene. The organization has 16586 authors who have published 35691 publications receiving 1095107 citations. The organization is also known as: Leibniz-Gemeinschaft & Wissenschaftsgemeinschaft Gottfried Wilhelm Leibniz.
Topics: Population, Gene, Aerosol, Catalysis, Genome
Papers published on a yearly basis
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TL;DR: Far more pronounced effects, compared to those obtained with pure toxins, were observed following exposure to various aqueous crude extracts of cyanobacteria from field samples and batch cultures: similar malformations combined with high mortalities and adverse effects on outer egg structures were observed concomitantly in all species.
Abstract: The effects of cyanobacterial hepatotoxins microcystin-LR, -RR, and -YR, of the neurotoxins saxitoxin and anatoxin-a, and of crude aqueous extracts of cyanobacteria were determined on the embryos of fish and amphibians from cleavage up to advanced stages of embryonic development. No acute toxic effects were observed after exposure to microcystins at 0.5, 5, and 50 μg/L, but the timing of hatching was altered in rainbow trout: earlier hatching occurred with 0.5, 5, and 50 μg/L microcystin-RR, 5 and 50 μg/L microcystin-YR, and 50 μg/L microcystin-LR; a minor delay in hatching was observed at 0.5 and 5 μg/L microcystin-LR. In axolotl, a delay in feeding was observed (microcystin-LR at 5 and 50 μg/L; microcystin-YR at 50 μg/L). After termination of exposure and rearing in toxin-free tanks, survival rate and growth were adversely affected in zebrafish larvae preexposed to microcystin-LR at 5 and 50 μg/L. At the highest applied concentration of microcystin-LR (10 mg/L), morphological effects were detected. Saxitoxin at 10 μg/L and above delayed hatching in zebrafish and led to malformations and mortalities at 500 μg/L. Hatching was also delayed in axolotl at 500 μg/L saxitoxin. Anatoxin-a (400 μg/L) altered the heart rate in zebrafish, but no chronic effects were observed. Far more pronounced effects, compared to those obtained with pure toxins, were observed following exposure to various aqueous crude extracts of cyanobacteria from field samples and batch cultures: similar malformations combined with high mortalities and adverse effects on outer egg structures were observed concomitantly in all species. HPLC data showed that these effects cannot be attributed to microcystin content alone. ©1999 John Wiley & Sons, Inc. Environ Toxicol 14: 77–88, 1999
211 citations
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Indiana University1, Laboratory of Molecular Biology2, Oregon State University3, Centre national de la recherche scientifique4, Texas A&M University5, Hungarian Academy of Sciences6, Scripps Research Institute7, University of Toronto8, University of Debrecen9, University of British Columbia10, Korea Research Institute of Bioscience and Biotechnology11, University College London12, Aix-Marseille University13, Georgetown University14, Osaka University15, Tel Aviv University16, Temple University17, Washington University in St. Louis18, Ludwig Maximilian University of Munich19, Leibniz Association20, University of Twente21, Weizmann Institute of Science22, Vrije Universiteit Brussel23, Russian Academy of Sciences24, University of South Florida25
TL;DR: In this paper, a series of publications on disambiguation of the basic terms used in the field of intrinsically disordered proteins is presented, starting from the explanation of what the expression "intrinsically disordered protein" actually means and why this particular term has been chosen as the common denominator for this class of proteins characterized by broad structural, dynamic and functional characteristics.
Abstract: "What's in a name? That which we call a rose By any other name would smell as sweet." From "Romeo and Juliet", William Shakespeare (1594) This article opens a series of publications on disambiguation of the basic terms used in the field of intrinsically disordered proteins. We start from the beginning, namely from the explanation of what the expression "intrinsically disordered protein" actually means and why this particular term has been chosen as the common denominator for this class of proteins characterized by broad structural, dynamic and functional characteristics.
211 citations
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TL;DR: In this article, the formation and initial growth process is almost exclusively driven by iodine oxoacids and iodine oxide vapours, with average oxygen-to-iodine ratios of 2.4 found in the clusters.
Abstract: Homogeneous nucleation and subsequent cluster growth leads to the formation of new aerosol particles in the atmosphere. The nucleation of sulfuric acid and organic vapours is thought to be responsible for the formation of new particles over continents, whereas iodine oxide vapours have been implicated in particle formation over coastal regions. The molecular clustering pathways that are involved in atmospheric particle formation have been elucidated in controlled laboratory studies of chemically simple systems, but direct molecular-level observations of nucleation in atmospheric field conditions that involve sulfuric acid, organic or iodine oxide vapours have yet to be reported. Here we present field data from Mace Head, Ireland, and supporting data from northern Greenland and Queen Maud Land, Antarctica, that enable us to identify the molecular steps involved in new particle formation in an iodine-rich, coastal atmospheric environment. We find that the formation and initial growth process is almost exclusively driven by iodine oxoacids and iodine oxide vapours, with average oxygen-to-iodine ratios of 2.4 found in the clusters. On the basis of this high ratio, together with the high concentrations of iodic acid (HIO3) observed, we suggest that cluster formation primarily proceeds by sequential addition of HIO3, followed by intracluster restructuring to I2O5 and recycling of water either in the atmosphere or on dehydration. Our study provides ambient atmospheric molecular-level observations of nucleation, supporting the previously suggested role of iodine-containing species in the formation of new aerosol particles, and identifies the key nucleating compound.
210 citations
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TL;DR: Suss et al. as discussed by the authors developed a next-generation electrochemical system for energy storage and water desalination applications at the Technion-Israel Institute of Technology (Technion).
210 citations
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210 citations
Authors
Showing all 16595 results
Name | H-index | Papers | Citations |
---|---|---|---|
Helmut Sies | 133 | 670 | 78319 |
Mark Stitt | 132 | 456 | 60800 |
Norbert Schwarz | 117 | 488 | 71008 |
Matthias Beller | 113 | 733 | 46344 |
Matthias Steinmetz | 112 | 461 | 67802 |
Marten Scheffer | 111 | 350 | 73789 |
Erko Stackebrandt | 106 | 633 | 68201 |
Andreas Radbruch | 104 | 485 | 36872 |
Rajeev K. Varshney | 102 | 709 | 39796 |
Thomas J. Jentsch | 101 | 238 | 32810 |
Michael Schulz | 100 | 759 | 50719 |
Oliver G. Schmidt | 100 | 1083 | 39988 |
Rainer Waser | 99 | 927 | 48315 |
Paul Knochel | 99 | 2373 | 44786 |
Matthias Beller | 97 | 903 | 34480 |