Loma Linda University

About: Loma Linda University is a education organization based out in Loma Linda, California, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 9220 authors who have published 13485 publications receiving 447094 citations. The organization is also known as: University of Loma Linda.

Mental health factors and intimate partner violence perpetration and victimization: a meta-analysis

Abstract: Objectives: This meta-analysis aimed to explore the relationship between mental health disorders and symptoms of mental health disorders (depression, anxiety, posttraumatic stress disorder [PTSD], antisocial personality disorder [PD], and borderline PD) and physical intimate partner violence (IPV) perpetration and victimization for males and females. Method: Data from 207 studies, yielding 511 effect sizes, were analyzed. The overall strength of each correlate for IPV perpetration and victimization was examined. Moderator analyses were used to compare the strength of correlates for IPV victimization versus perpetration, as well as for males versus females. Results: Depression, anxiety, PTSD, antisocial PD, and borderline PD were all significant correlates for both IPV victimization and perpetration. Anxiety and PTSD were significantly stronger correlates for victimization than for perpetration, and borderline PD and antisocial PD were significantly stronger correlates for perpetration than for victimization. For women, borderline PD was a significantly stronger correlate for IPV perpetration than for victimization, and PTSD was a significantly stronger correlate for IPV victimization than perpetration. Depression was a significantly stronger correlate for IPV victimization for women than for men. Conclusions: This study provides a comprehensive examination of mental health disorders and their link to IPV perpetration and victimization. The results suggest that clinicians working with individuals or couples in the context of IPV should assess for and treat mental health problems.

Criteria for Selection of Surrogates Used To Study the Fate and Control of Pathogens in the Environment

Abstract: This article defines the term surrogate as an organism, particle, or substance used to study the fate of a pathogen in a specific environment. Pathogenic organisms, nonpathogenic organisms, and innocuous particles have been used as surrogates for a variety of purposes, including studies on survival and transport as well as for method development and as "indicators" of certain conditions. This article develops a qualitative surrogate attribute prioritization process and allows investigators to select a surrogate by systematically detailing the experimental process and prioritizing attributes. The results are described through the use of case studies of various laboratories that have used this process. This article also discusses the history of surrogate and microbial indicator use and outlines the method by which surrogates can be used when conducting a quantitative microbial risk assessment. The ultimate goal of selecting a sufficiently representative surrogate is to improve public health through a health-based risk assessment framework. Under- or overestimating the resistance, inactivation, or movement may negatively impact risk assessments that, in turn, will impact health assessments and estimated safety levels. Reducing uncertainty in a risk assessment is one of the objectives of using surrogates and the ultimate motive for any experiment investigating potential exposure of a pathogen.

Suppression of LDL oxidation by garlic.

Abstract: It has been known for several decades that hypercholesterolemia is a major risk factor for atherosclerosis and that lowering of cholesterol can significantly reduce risk for cardiovascular diseases. More recently, oxidation of LDL has been recognized as playing an important role in the initiation and progression of atherosclerosis. Oxidized LDL, but not native LDL, promotes vascular dysfunction by exerting direct cytotoxicity toward endothelial cells, by increasing chemotactic properties for monocytes, by transforming macrophages to foam cells via scavenger-receptors and by enhancing the proliferation of various cell types, e.g., endothelial cells, monocytes and smooth muscle cells; all of these events are recognized as contributing to atherogenesis. In this paper, experimental evidence is presented that shows that several garlic compounds can effectively suppress LDL oxidation in vitro. Short-term supplementation of garlic in human subjects has demonstrated an increased resistance of LDL to oxidation. These data suggest that suppressed LDL oxidation may be one of the powerful mechanisms accounting for the antiatherosclerotic properties of garlic.

A Cognition (Attribution)-Emotion Model of Violence in Conflict Situations

Abstract: The present research was designed to examine the relationships between attribution processes and interpersonal emotions (anger and empathic emotions) as determinants of violent reactions in conflict situations. A model including the mediating role of attribution processes and emotions as well as all theoretically meaningful relationships among the variables was proposed and tested using Bentler's structural equations program (EQS). Results show that the model fits the data well and the mediating role of anger and empathic emotions is supported In addition, the role of attributional thinking (e.g., perceived intentionality of an instigation and controllability of its cause) as a determinant of anger and empathic emotions is confirmed. Results are discussed in terms of potential extensions and applications of attribution theory and the role of interpersonal emotions in antisocial behavior and interpersonal relations in general