Institution
Loma Linda University
Education•Loma Linda, California, United States•
About: Loma Linda University is a education organization based out in Loma Linda, California, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 9220 authors who have published 13485 publications receiving 447094 citations. The organization is also known as: University of Loma Linda.
Topics: Population, Medicine, Poison control, Transplantation, Health care
Papers published on a yearly basis
Papers
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TL;DR: Findings suggest that the PFSDQ-M demonstrates initial reliability; good validity estimates, as seen with the factor analysis, and the dyspnea and activity scores appear responsive to physiologic changes in lung function over time.
178 citations
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TL;DR: Although this syndrome has several distinctive features, including age distribution and apparent occurrence during sleep, there has been reluctance to include these features in the definition, and a 2-tiered approach is suggested, with a more general definition intended primarily for case management and death administration.
Abstract: Sudden infant death syndrome (SIDS) is a term that was first proposed in 1969 for a distinctive subgroup of unexpected infant deaths that occur during the postneonatal period with relatively consistent clinical, epidemiological, and pathological features. This term played an important role by focusing attention on a major category of postneonatal infant death, providing support to grieving families, and diminishing the guilt and blame characteristic of these deaths. Unfortunately, the application of this term has become increasingly controversial. Some have applied it too liberally, and others not at all. According to the definition proposed in 1969, despite slight changes suggested in 1989, SIDS remains a diagnosis of exclusion. Although this syndrome has several distinctive features, including age distribution and apparent occurrence during sleep, there has been reluctance to include these features in the definition. The problems created by the lack of an adequate definition are discussed. A 2-tiered approach is suggested, with a more general definition intended primarily for case management and death administration, and a more restrictive one intended primarily for research purposes, which distinguishes those deaths closely fitting the classic SIDS profile from those with one or more less typical features.
177 citations
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TL;DR: The results showed that the corticotomy procedure caused minimal changes in the periodontal attachment apparatus.
Abstract: This report describes the corticotomy surgical technique used in conjunction with orthodontic therapy and its effect on the periodontal status of the involved teeth. The surgical procedure included intracrevicular incisions and elevation of buccal and lingual mucoperiosteal flaps. Buccal and lingual vertical grooves penetrating the cortical bone were then made between the roots. These grooves were extended from just below the interproximal alveolar bone margin to beyond the apex levels of the teeth. Buccal and lingual horizontal grooves joined the apical extensions of the vertical grooves. The orthodontic appliance was activated immediately upon wound closure. Plaque scores, probing depths, and probing attachment levels were recorded before the surgical procedure and after the completion of the orthodontic treatment in 5 patients. The results showed that the corticotomy procedure caused minimal changes in the periodontal attachment apparatus.
177 citations
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TL;DR: Isoenergetic incorporation of approximately 68 g of almonds into an 8368-kJ (2000-kcal) Step I diet markedly improved the serum lipid profile of healthy and mildly hypercholesterolemic adults.
177 citations
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TL;DR: The results are consistent with a role of cannabinoid receptors in the modulation of dopamine and cannabinoid reward pathways and the association with specific types of drug dependence was greatest for cocaine, amphetamine, and cannabis dependence.
Abstract: The receptors for tetrahydrocannabinol, the active ingredient of marijuana, have been identified. A microsatellite polymorphism (AAT)n at the cannabinoid CB1 (brain) receptor gene (CNR1) consists of 9 alleles. Since the cannabinoid system is part of the reward pathway we examined the hypothesis that genetic variants of the CNR1 gene might be associated with susceptibility to alcohol or drug dependence. The study consisted of 92 subjects on an Addiction Treatment Unit (ATU) and 114 controls. All were non-Hispanic Caucasians. The ATU subjects were screened for all types of substance dependence using the Diagnostic Interview Schedule (DIS), and for a variety of substance abuse symptoms using the Addiction Severity Index (ASI). Since inspection of the distribution of alleles in controls vs i.v. drug use showed a decrease in the frequency of the 4 allele, and the or =/> or = 5. When all variables were subjected to factor analysis, factor 1 showed a clustering of drug dependence variables and factor 2 of alcohol dependence variables. By ANOVA only factor 1 showed significant differences by genotype consistent with a model where homozygosity for the > or = 5 repeat alleles showed the greatest effect. The number of i.v. drugs used was significantly greater for those carrying the > or =/> or = 5 genotype than for other genotypes (P = 0.005). The association with specific types of drug dependence was greatest for cocaine, amphetamine, and cannabis dependence. The results are consistent with a role of cannabinoid receptors in the modulation of dopamine and cannabinoid reward pathways. Independent studies should be designed to further confirm the hypothesis that cannabinoid receptors may contribute to the susceptibility to drug abuse.
177 citations
Authors
Showing all 9287 results
Name | H-index | Papers | Citations |
---|---|---|---|
Bruce L. Miller | 163 | 1153 | 115975 |
Jonathan I. Epstein | 138 | 1121 | 80975 |
Tony L. Yaksh | 123 | 806 | 60898 |
David M. Livingston | 118 | 312 | 58142 |
William B. Isaacs | 117 | 521 | 58187 |
Alan W. Partin | 111 | 710 | 54213 |
David N. Herndon | 108 | 1227 | 54888 |
Edward R. Laws | 105 | 722 | 39822 |
David C. Bellinger | 98 | 452 | 35449 |
Pedram Argani | 97 | 372 | 35607 |
Michael W. Steffes | 96 | 341 | 43260 |
Gary K. Steinberg | 94 | 529 | 31259 |
Michael S. Gazzaniga | 92 | 372 | 35305 |
David J. Baylink | 90 | 425 | 29109 |
Jesse B. Jupiter | 90 | 543 | 26480 |