Institution
Loma Linda University
Education•Loma Linda, California, United States•
About: Loma Linda University is a education organization based out in Loma Linda, California, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 9220 authors who have published 13485 publications receiving 447094 citations. The organization is also known as: University of Loma Linda.
Topics: Population, Medicine, Poison control, Transplantation, Health care
Papers published on a yearly basis
Papers
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TL;DR: Seven neuroprotective core measures for family-centered developmental care of the premature neonate are addressed: healing environment, partnering with families, positioning and handling, minimizing stress and pain, safeguarding sleep, protecting skin, and optimizing nutrition.
126 citations
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TL;DR: Electrophysiologic, morphologic, and in vitro data conclusively demonstrate that salicylate affects outer hair cells, andSalicylates and NSAIDs inhibit PG-forming cyclooxygenase, and recent studies suggest that abnormal levels of arachidonic acid metabolites consisting of decreased PGs and increased LTs may mediate salicYLate ototoxicity.
126 citations
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TL;DR: The addition of rhBMP-2 may aid in its success rate by promoting osteogenesis at the osteotomy site, especially in multiple-operated patients where other traditional techniques have failed to gain the desired ridge height.
Abstract: The goal of this study was to demonstrate the technique and effectiveness of incorporating recombinant human bone morphogenetic protein-2 (rhBMP-2) to the established sandwich osteotomy technique. Although the success of the sandwich osteotomy procedure has been well documented, we hope to show that the addition of rhBMP-2 will enhance bone formation.We performed a sandwich osteotomy technique in patients who had been treated initially by grafting with suboptimal results. Only defects involving the anterior maxilla (3 patients) or the anterior mandible (1 patient) were included. There were 4 patients, 2 men and 2 women, with an age range of 19 to 62 years. The causes of the ridge deficiencies ranged from pathology to trauma. The height (distance) of distracted transport bone segment was measured. The amount of relapse was measured 6 months after the surgery.All patients exhibited a significant increase in bone height. The amount distracted was 6.75 mm (range, 5-11 mm). The amount of relapse was 8.5% (range, 0%-18%). Dental implants were placed in the reconstructed ridges in all patients. There were no instances of permanent paresthesia. Two patients had exposure of a portion of the hardware, which healed uneventfully.The sandwich osteotomy technique has proven to be an effective method for augmenting deficient alveolar ridges. The addition of rhBMP-2 may aid in its success rate by promoting osteogenesis at the osteotomy site, especially in multiple-operated patients where other traditional techniques have failed to gain the desired ridge height.
126 citations
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TL;DR: An in vitro model incorporating a low‐amplitude, low frequency, capacitively coupled electric field, found that electric field‐stimulated human bone cell proliferation was associated with increased IGF‐II mRNA accumulation and IGF-II secretion suggesting that IGF‐ II may in part mediate the increase in bone celliferation following electric field exposure.
Abstract: We have developed an in vitro model incorporating a low-amplitude (10(-7) V/cm), low frequency (f less than 100 Hz), capacitively coupled electric field in order to study the mechanism through which an electric field may increase bone cell proliferation. Utilizing this model we have previously shown that electric field-stimulated bone cell proliferation was dependent on release of mitogen activity into the culture medium from exposed cells. The current studies were intended to characterize this mitogen activity. In these studies we found that electric field-stimulated human bone cell proliferation was associated with increased IGF-II mRNA accumulation and IGF-II secretion suggesting that IGF-II may in part mediate the increase in bone cell proliferation following electric field exposure.
126 citations
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TL;DR: The data show that young children with VCFS show a receptive-expressive language impairment from the onset of language and were severely delayed beyond a level predicted by their other developmental or receptive language performance.
Abstract: Speech–language impairment is one of the most common clinical features in velocardiofacial syndrome (VCFS). This report describes the speech and language development of four children with VCFS studied longitudinally from 6 to 30 months of age and compares their performance with three groups of children: (1) normally developing children, (2) children with cleft lip and palate, and (3) children with isolated cleft palate. The data show that young children with VCFS show a receptive-expressive language impairment from the onset of language. Further, speech and expressive language development were severely delayed beyond a level predicted by their other developmental or receptive language performance. The children with VCFS showed severe limitations in speech sound inventories and early vocabulary development that far exceeded those shown by the children with cleft lip and palate and children with isolated cleft palate. This study indicates that young children with VCFS emerge from a critical speech and language learning period with severe limitations in their communicative abilities. Further studies are required to describe the later course of these early speech and language impairments and to explore the relationship to learning disabilities described for older children with VCFS. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:714–723, 1999. © 1999 Wiley-Liss, Inc.
126 citations
Authors
Showing all 9287 results
Name | H-index | Papers | Citations |
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Bruce L. Miller | 163 | 1153 | 115975 |
Jonathan I. Epstein | 138 | 1121 | 80975 |
Tony L. Yaksh | 123 | 806 | 60898 |
David M. Livingston | 118 | 312 | 58142 |
William B. Isaacs | 117 | 521 | 58187 |
Alan W. Partin | 111 | 710 | 54213 |
David N. Herndon | 108 | 1227 | 54888 |
Edward R. Laws | 105 | 722 | 39822 |
David C. Bellinger | 98 | 452 | 35449 |
Pedram Argani | 97 | 372 | 35607 |
Michael W. Steffes | 96 | 341 | 43260 |
Gary K. Steinberg | 94 | 529 | 31259 |
Michael S. Gazzaniga | 92 | 372 | 35305 |
David J. Baylink | 90 | 425 | 29109 |
Jesse B. Jupiter | 90 | 543 | 26480 |