Institution
University of Maryland Biotechnology Institute
About: University of Maryland Biotechnology Institute is a based out in . It is known for research contribution in the topics: Gene & Population. The organization has 1565 authors who have published 2458 publications receiving 171434 citations. The organization is also known as: UMBI.
Topics: Gene, Population, Protein structure, Receptor, Peptide sequence
Papers published on a yearly basis
Papers
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TL;DR: It is shown that nanostructured electrically conductive polymer polypyrrole substantially improved the efficiency of electron collection from photosynthetic biofilm in PMFCs.
85 citations
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TL;DR: The results demonstrate that GnRHa administration via controlled delivery systems is an effective method for producing good quality eggs in captive dusky grouper.
85 citations
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TL;DR: It was demonstrated that glycosylation influenced the global conformations of the V3 domain and provided protection of theV3 domain against protease digestion.
Abstract: A highly efficient chemoenzymatic synthesis of HIV-1 V3 domain glycopeptides carrying two N-linked core tri- and pentasaccharides was achieved. The synthesis consisted of two key steps: a solid-phase synthesis of the cyclic, 47-mer V3 domain peptide containing two GlcNAc residues and a novel endoglycosidase-catalyzed transglycosylation that simultaneously added two N-glycan moieties to the peptide precursor from the oligosaccharide oxazoline donor substrates. The availability of the synthetic glycopeptides allowed the probing of the effects of glycosylation on the HIV-1 V3 domain. It was demonstrated that glycosylation influenced the global conformations of the V3 domain and provided protection of the V3 domain against protease digestion.
85 citations
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TL;DR: Culture-based and molecular techniques showed an increase in the Bacteroidetes and Alpha- and Gammaproteobacteria components of the bacterial community in aquaculture.
Abstract: Marine sponges in the genus Ircinia are known to be good sources of secondary metabolites with biological activities. A major obstacle in the development of sponge-derived metabolites is the difficulty in ensuring an economic, sustainable supply of the metabolites. A promising strategy is the ex situ culture of sponges in closed or semiclosed aquaculture systems. In this study, the marine sponge Ircinia strobilina (order Dictyoceratida: family Irciniidae) was collected from the wild and maintained for a year in a recirculating aquaculture system. Microbiological and molecular community analyses were performed on freshly collected sponges and sponges maintained in aquaculture for 3 months and 9 months. Chemical analyses were performed on wild collected sponges and individuals maintained in aquaculture for 3 months and 1 year. Denaturing gradient gel electrophoresis was used to assess the complexity of and to monitor changes in the microbial communities associated with I. strobilina. Culture-based and molecular techniques showed an increase in the Bacteroidetes and Alpha- and Gammaproteobacteria components of the bacterial community in aquaculture. Populations affiliated with Beta- and Deltaproteobacteria, Clostridia, and Planctomycetes emerged in sponges maintained in aquaculture. The diversity of bacterial communities increased upon transfer into aquaculture.
85 citations
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TL;DR: This Re complex was conjugated to several biomolecules, including the proteins human serum albumin and bovine immunoglobulin G, as well as an amine-containing lipid, and utilize it as biomolecular probe in a variety of environments.
85 citations
Authors
Showing all 1565 results
Name | H-index | Papers | Citations |
---|---|---|---|
Stanley B. Prusiner | 168 | 745 | 97528 |
Robert C. Gallo | 145 | 825 | 68212 |
Thomas J. Smith | 140 | 1775 | 113919 |
J. D. Hansen | 122 | 975 | 76198 |
Stephen Mann | 120 | 669 | 55008 |
Donald M. Bers | 118 | 570 | 52757 |
Jon Clardy | 116 | 983 | 56617 |
Rita R. Colwell | 115 | 781 | 55229 |
Joseph R. Lakowicz | 104 | 850 | 76257 |
Patrick M. Schlievert | 90 | 444 | 32037 |
Mitsuhiko Ikura | 89 | 316 | 34132 |
Jeremy Thorner | 87 | 234 | 29999 |
Lawrence E. Samelson | 87 | 209 | 27398 |
Jacques Ravel | 86 | 323 | 45793 |
W. J. Lederer | 79 | 213 | 25509 |