Showing papers in "Cytokine in 2006"

TL;DR: It is observed that the exopolysaccharide induced a gut mucosal response and it was able to up and down regulate it for protective immunity, maintaining intestinal homeostasis, enhancing the IgA production at both the small and large intestine level and influencing the systemic immunity through the cytokines released to the circulating blood.

TL;DR: Adiponectin was not related to age, disease duration, body mass index, or disease activity of RA patients, indicating that peripheral fat stores are major producers of adiponectIn into the blood stream, however, increased synovial fluid adip onectin in RA patients may counterpart the local inflammatory process.

TL;DR: There is an early increase of neutrophil CD64 expression and IL-8 levels during sepsis, and based on this single measurement it is possible to reliably assess the stage, detect the severity and predict the 28-day mortality of sepsi.

TL;DR: Serum TNF-alpha and IL-6 are sensitive markers of SLE disease activity and may be useful independent markers for prediction of Slemish Lupus Erythmatosus diseaseactivity and to differentiate normal subjects from those having SLE.

TL;DR: Serum and urine IL-6 in children with acute pyelonephritis were positively correlated with fever, CRP and leucocyturia, and indicate that both serum and urine Il-6 and IL-8 levels are useful diagnostic tools for early recognition of acute pyelsis in febrile children.

TL;DR: It is demonstrated that pentacyclic triterpenes in orujo oil exhibit pro- and anti-inflammatory properties depending on chemical structure and dose, and may be useful in modulating the immune response.

TL;DR: It is concluded that SEPS1 is a new target gene of NF-kappaB, a regulatory loop between cytokine production in macrophage cells, that plays a key role in control of the inflammatory response.

TL;DR: Present data highlight that, in an acute model of infection, UCP2 modulates innate immunity, via the modulation of ROS production, cytokine and chemokine production and consequently phagocyte recruitment.

TL;DR: Genetic variations in the VEGF may predict not only PCa risk but also tumor aggressiveness.

TL;DR: The results suggest that the polymorphisms in IL-10 gene may affect susceptibility to TB and increase risk of developing the disease, and further studies should be performed on other population groups.

TL;DR: In this article, the association between resistin and adiponectin levels and the presence of coronary artery disease (CAD) or diabetes compared to the controls was evaluated in 57 subjects with CAD, 58 subjects with diabetes, and 45 normal control subjects.

TL;DR: It is demonstrated that IL-18 is able to act synergistically with IL-15 in stimulating in vitro NK cell proliferation and raises the possibility thatIL-18 may act synergistic with IL -15 in driving pathogen-inducedNK cell proliferation in addition to its contribution in enhancing IL-12 stimulation of NK cell IFNgamma production.

TL;DR: The data on the use of anti-TNF drugs in uveitis is presented together with new data on its role as a steroid sparing agent.

TL;DR: It is demonstrated that IL-6 and TNF-α are regulated differentially in skeletal muscle cells in response to a Ca2+ stimulus, and blocking the calcineurin pathway resulted in inhibition of theIL-6 response to ionomycin, whereas TNF's gene expression increased by addition of CSA.

TL;DR: It can be concluded that the initiation and progression of periodontal inflammation may be due to a lack or inappropriate response of the anti-inflammatory cytokines in both CP and RA.

TL;DR: Data suggest that IL-1 is likely to be an important mediator in the initiation and maintenance of psoriatic plaques and may represent an attractive therapeutic target.

TL;DR: This study demonstrates an increase of sCXCL10 and sCCL2 with advancing age, which may reflect a general shift towards Th1 or Th2 cytokines pattern, respectively.

TL;DR: The combination of whole blood cultures with multiplex analysis is a simple and powerful tool that can be used to identify detailed cytokine profiles of specific cell-mediated immune responses.

TL;DR: It is demonstrated for the first time that LIF expression in loaded skeletal muscle is critical for the development of skeletal muscle hypertrophy in the functional overload model.

TL;DR: Peripheral blood production of interleukin-1α and tumor necrosis factor-α and TNF-α was studied in relation to the severity of histological changes of the liver in obese NAFLD patients to study enhanced pro-inflammatory cytokine production.

TL;DR: Inhibition of AR by three distinct AR inhibitors suppressed the LPS-induced production of inflammatory cytokines and prevented the production of nitric oxide, and prostaglandin E2 and expression of iNOS and Cox-2 proteins.

TL;DR: It is concluded that, while the relationships between inherited variations in IL-10 or T NF-alpha expression are not associated with alterations in HCV clearance or ALT levels, TNF-alpha polymorphisms may be associated with hepatic fibrosis.

TL;DR: The modulatory capacity of KF on the immune response in mammary glands and tumours is demonstrated and the importance of the administration period to obtain this effect is demonstrated.

TL;DR: It is found that administration of anti-4-1BB mAb induced massive clonal expansion of CD11c+CD8+ T cells that produced IFN-gamma, resulting in accumulation of a high level of indoleamine 2,3-dioxygenase (IDO) in CD 11c+ dendritic cells.

TL;DR: A proteasome inhibitor was utilized to maintain nuclear translocation of NF-kappaB at constitutive levels; its effect on IRF-1 expression and IDO-specific transcription was evaluated, suggesting that increases in NF- kappaB translocation are required for synergistic IDO expression in response to IFN-gamma and TNF-alpha.

TL;DR: The results suggest that high concentrations of either IL-2 or IL-15 will activate the lytic capacity and granzyme B expression of many T cells and that antigen recognition is not required.

TL;DR: It is demonstrated that OSM induces a motile/invasive phenotype in T-47D cells in vitro, and the results suggest thatOSM itself may be a valid therapeutic target and enhance metastasis in vivo.

TL;DR: Although the concentration of tear cytokines varied widely among eyes, the amount of cytokine had a specific alteration pattern in each eye during the course of a day with a specific pattern.

TL;DR: HIV-1-infected patients with clinically manifest LD are at higher risk for atherosclerosis and the relationship between inflammation and atherosclerotic disease is supported.

TL;DR: Results suggest that TNF-alpha-induced increase in apoptosis in ARVM results from caspase-8-dependent impairment of mitochondrial integrity.